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乙型肝炎疫苗接种覆盖率及相关因素:2019 - 2020年在北京开展的一项基于社区的横断面研究

Hepatitis B Vaccination Coverage Rates and Associated Factors: A Community-Based, Cross-Sectional Study Conducted in Beijing, 2019-2020.

作者信息

Liang Yan, Bai Xinxin, Liu Xinyao, Zhang Zheng, Pang Xinghuo, Nie Li, Qiu Wuqi, Zhao Wei, Hu Guangyu

机构信息

Chaoyang District Center for Disease Prevention and Control of Beijing, Beijing 100020, China.

School of Public Health, Hebei Medical University, Shijiazhuang 050011, China.

出版信息

Vaccines (Basel). 2021 Sep 24;9(10):1070. doi: 10.3390/vaccines9101070.

Abstract

Hepatitis B vaccination coverage rates are low throughout most populations in China. Factors influencing low coverage rates, including population-specific hepatitis B vaccination barriers, may inform policies that promote vaccination. A cross-sectional survey of residents from 43 communities assessed their vaccination status and identified associated factors via uni- and multivariable logistic regression and subgroup analyses. In total, 11,280 of 36,007 respondents received a hepatitis B vaccine, indicating a 31.33% coverage rate. Multivariable logistic regression revealed non-Beijing (odds ratio (OR) = 0.81; 95% confidence interval (CI): 0.76-0.85) and residents who self-rated their health as very healthy (OR = 0.82; 95% CI: 0.68-0.99) were unlikely to be vaccinated. Farmers (OR = 1.68; 95% CI: 1.51-1.86), commerce and service workers (OR = 1.82; 95% CI, 1.63-2.04), government employees (OR = 1.56; 95% CI: 1.38-1.77), professionals and technicians (OR = 1.85; 95% CI: 1.63-2.09), and students (OR = 1.69; 95% CI: 1.10-2.59) had increased hepatitis B vaccination rates. The multivariable assessment revealed hepatitis B vaccination coverage rates are associated with confirmed or suspected family cases, vaccination unwillingness or uncertainty, and unawareness of its prevention of the hepatitis B virus. Low hepatitis B vaccination coverage rates among Beijing subpopulations highlight the need for improved strategies, including those that target specific populations.

摘要

在中国,大多数人群的乙肝疫苗接种率较低。影响接种率低的因素,包括特定人群的乙肝疫苗接种障碍,可为促进疫苗接种的政策提供参考。一项对43个社区居民的横断面调查评估了他们的疫苗接种状况,并通过单变量和多变量逻辑回归以及亚组分析确定了相关因素。在36,007名受访者中,共有11,280人接种了乙肝疫苗,接种率为31.33%。多变量逻辑回归显示,非北京地区居民(优势比(OR)=0.81;95%置信区间(CI):0.76-0.85)以及自评为非常健康的居民(OR =0.82;95%CI:0.68-0.99)不太可能接种疫苗。农民(OR =1.68;95%CI:1.51-1.86)、商业和服务业工人(OR =1.82;95%CI,1.63-2.04)、政府雇员(OR =1.56;95%CI:1.38-1.77)、专业技术人员(OR =1.85;95%CI:1.63-2.09)和学生(OR =1.69;95%CI:1.10-2.59)的乙肝疫苗接种率有所提高。多变量评估显示,乙肝疫苗接种率与确诊或疑似家庭病例、接种意愿或不确定性以及对预防乙肝病毒的认识不足有关。北京亚人群中乙肝疫苗接种率较低,这凸显了改进策略的必要性,包括针对特定人群的策略。

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