Hospital Universitario Virgen de la Luz, Cuenca, Spain.
Hospital General Universitario de Castellón, Castellón, Spain.
An Pediatr (Engl Ed). 2021 Nov;95(5):345-353. doi: 10.1016/j.anpede.2021.06.006. Epub 2021 Oct 23.
Non-pharmaceutical interventions that have been implemented in southern hemisphere countries because of COVID-19 pandemic declaration in March 2020, have evidenced some unexpected changes in the way of spreading of many other viruses. This study as a part of ECEALHBA's Project, reports the consequences of COVID-19 pandemic over 2020-2021 bronchiolitis epidemic period in the Central and Eastern regions of Spain.
Multicenter, observational, descriptive and ambispective study of admitted infants with the diagnosis of bronchiolitis in 16 Spanish hospitals involved in the investigation project. Five epidemic periods previous to COVID-19 pandemic, from 2015 to 2020, were compared with the current one, 2020-2021, in both a qualitative and quantitative manner.
Total of 4643 infants were admitted to the participating hospitals along the study period. Pandemic season hospital admissions for bronchiolitis were 94.1% lower than in pre-pandemic period. December and January were peak months for bronchiolitis admissions during pre-pandemic period, but September was the peak month during pandemic year. There was a progressive decrease of admissions from this moment until the end of the follow-up, in April 2021. Rhinovirus has been the commonest etiology for bronchiolitis in 2020-2021 epidemic period of bronchiolitis.
Some of the non-pharmaceutical interventions initiated because of COVID-19 pandemic are probably related to the dramatic decrease of bronchiolitis cases in 2020-2021 season. It would be rewarding to purpose novel research to clarify how these simple interventions can be useful, close to vaccines and antiviral drugs, to achieve the goal of avoiding the spread of respiratory viruses in pediatric population.
由于 2020 年 3 月宣布 COVID-19 大流行,南半球国家实施了非药物干预措施,这使得许多其他病毒的传播方式发生了一些意想不到的变化。本研究作为 ECEALHBA 项目的一部分,报告了 COVID-19 大流行对西班牙中东部地区 2020-2021 年毛细支气管炎流行期间的影响。
对参与调查项目的 16 家西班牙医院收治的毛细支气管炎患儿进行多中心、观察性、描述性和前瞻性研究。以定性和定量的方式比较了 COVID-19 大流行前的五个流行期(2015 年至 2020 年)与当前流行期(2020-2021 年)。
研究期间,共有 4643 名婴儿入住参与医院。大流行季节毛细支气管炎住院人数比大流行前减少 94.1%。大流行前,12 月和 1 月是毛细支气管炎住院高峰期,而大流行年 9 月是高峰期。此后,入院人数逐月减少,直至 2021 年 4 月随访结束。呼吸道合胞病毒是 2020-2021 年毛细支气管炎流行期间毛细支气管炎的常见病因。
由于 COVID-19 大流行而启动的一些非药物干预措施可能与 2020-2021 年季节毛细支气管炎病例的急剧减少有关。值得提出新的研究,以阐明这些简单的干预措施如何像疫苗和抗病毒药物一样,有助于实现避免儿科人群呼吸道病毒传播的目标。