Faculty of Health and Medical Sciences, Section of Epidemiology, University of Copenhagen, Øster Farimagsgade 5A, Box 2099, 1014, Copenhagen K, Denmark.
Department of Gynecology and Obstetrics, Holbæk Hospital, Smedelundsgade 60, 4300, Holbæk, Denmark.
Sci Rep. 2021 Oct 25;11(1):21021. doi: 10.1038/s41598-021-00482-5.
The aim of this study was to examine associations between selected sociodemographic, socioeconomic, and health characteristics and the rates of fatherhood in different age groups. We investigated rates between 2011 and 2015 in a population-based register study including all men born from 1945 to 1995 residing in Denmark in 2011. The study population consisted of 1,867,108 men who fathered 268,612 children during the follow-up. The associations were quantified as incidence rate ratios using Poisson regression. Young men had higher rates of fathering a child if they lived outside the Capital Region, had a relatively high income, were previously diagnosed with cardiovascular disease, psychoactive substance abuse, personality disorders, schizophrenia or behavioural and emotional disorders. Men of advanced age had higher rates of fathering a child when born outside Denmark, living in the Capital Region, were in the lower or upper 10th percentile income group, were self-employed or unemployed or previously diagnosed with depression. Men of advanced age had lower rates of fathering a child if previously diagnosed with somatic diseases, psychoactive substance abuse or mental retardation. The findings highlight the importance of consideration of various sociodemographic, socioeconomic, and health characteristics when studying associations between paternal age and offspring health.
本研究旨在探讨特定社会人口学、社会经济学和健康特征与不同年龄组父亲身份率之间的关联。我们在一项基于人群的注册研究中调查了 2011 年至 2015 年之间的比率，该研究包括了 2011 年居住在丹麦的所有 1945 年至 1995 年出生的男性。研究人群由 1867108 名男性组成，他们在随访期间生育了 268612 名子女。使用泊松回归定量了关联，结果表示为发病率比率。如果年轻男性居住在首都地区以外、收入相对较高、以前被诊断患有心血管疾病、精神活性物质滥用、人格障碍、精神分裂症或行为和情感障碍，则他们生育子女的比率较高。如果男性在丹麦境外出生、居住在首都地区、处于收入较低或较高的第 10 百分位数组、自雇或失业或以前被诊断患有抑郁症，则年龄较大的男性生育子女的比率较高。如果以前被诊断患有躯体疾病、精神活性物质滥用或智力迟钝，则年龄较大的男性生育子女的比率较低。这些发现强调了在研究父亲年龄与后代健康之间的关联时，考虑各种社会人口学、社会经济学和健康特征的重要性。
