Antibiotics are often effective in curing a patient of his infection even when used in a suboptimal manner. In this situation it is often difficult for the prescriber to accept that he/she is using antibiotics "badly" when he can point to the majority of his infections responding well--either to the antibiotic or the patient's own immune response. Many attempts have been made to limit antibiotic use by selective laboratory reporting, by restricting the antibiotics available, by producing guidelines for initial therapy of infection or prophylaxis, by involvement of infectious disease specialists in all antibiotic use and by several other systems. It appears, however, that antibiotic use is still heavily criticised and is a continuing source of conflict in medicine. Consensus on antibiotic indications is still difficult to obtain and is likely to be achieved very slowly. It is clear that polemic is not sufficient and that consensus practices can only be based upon firm scientifically acquired data and detailed discussion of the options by those most intimately involved.
抗生素即使以次优方式使用,通常也能有效治愈患者的感染。在这种情况下,开药者往往难以接受自己“不合理”使用抗生素,因为他/她可以指出大多数感染对抗生素或患者自身免疫反应的反应良好。人们已经进行了许多尝试来限制抗生素的使用,包括通过选择性实验室报告、限制可用抗生素、制定感染初始治疗或预防指南、让传染病专家参与所有抗生素使用以及其他一些系统。然而,抗生素的使用似乎仍然受到严厉批评,并且仍然是医学领域持续冲突的根源。关于抗生素适应症的共识仍然难以达成,而且可能进展非常缓慢。显然,争论是不够的,共识做法只能基于可靠的科学数据以及最密切相关人员对各种选择的详细讨论。