Jorke D, Bach G
Z Gesamte Inn Med. 1986 Nov 1;41(21):595-8.
From the viewpoint of a territorial haematological centre with a certainly preselected number of patients the initial symptom of bi- or pancytopenia in 3/4 of the cases proves as first reference to a myeloproliferative or myelodysplastic syndrome. Of these cases 62.5% transferred into a crisis of blasts; that is, they must be regarded as real preleukemia. The morphology of the bone marrow as well as the stem cell cultures obtained from this give important references to the diagnostic classification of the early changes as well as to their prognosis.
从一个有一定预先选定患者数量的地区血液学中心的角度来看,在3/4的病例中,双系或全血细胞减少的初始症状被证明是骨髓增殖性或骨髓增生异常综合征的首要参考指标。在这些病例中,62.5%转变为原始细胞危象;也就是说,它们必须被视为真正的白血病前期。骨髓形态以及从中获得的干细胞培养物为早期变化的诊断分类及其预后提供了重要参考。