Mayo Clinic Alix School of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Acad Emerg Med. 2022 Jan;29(1):6-14. doi: 10.1111/acem.14406. Epub 2021 Nov 9.
Many guidelines for septic olecranon bursitis recommend aspiration of the bursa prior to initiation of antimicrobial therapy despite the absence of robust clinical data to support this practice and known risk of aspiration complications. Our objective was to describe outcomes associated with empiric antibiotic therapy without bursal aspiration among emergency department (ED) patients with suspected septic olecranon bursitis.
We conducted a retrospective observational cohort study of patients presenting to an academic ED from January 1, 2011, to December 31, 2018, with olecranon bursitis. The health record was reviewed to assess patient characteristics and outcomes within 6 months of the ED visit. Olecranon bursitis was considered "suspected septic" if the patient was treated with antibiotics. The primary outcome of interest was complicated versus uncomplicated bursitis resolution. Uncomplicated resolution was defined as bursitis resolution without subsequent bursal aspiration, surgery, or hospitalization.
During the study period, 264 ED patients were evaluated for 266 cases of olecranon bursitis. The median age was 57 years and 85% were men. Four (1.5%) patients had bursal aspiration during their ED visit, 39 (14.7%) were admitted to the hospital, 76 (28.6%) were dismissed without antibiotic therapy, and 147 (55.3%) were dismissed with empiric antibiotic therapy for suspected septic olecranon bursitis. Among these 147 patients, 134 had follow-up available including 118 (88.1%, 95% confidence interval [CI] = 81.1%-92.8%) with an uncomplicated resolution, eight (6.0%, 95% CI = 2.8%-11.8%) who underwent subsequent bursal aspiration, and nine (6.7%, 95% CI = 3.3%-12.7%) who were subsequently admitted for inpatient antibiotics.
Eighty-eight percent of ED patients with suspected septic olecranon bursitis treated with empiric antibiotics without aspiration had resolution without need for subsequent bursal aspiration, hospitalization, or surgery. Our findings suggest that empiric antibiotics without bursal aspiration may be a reasonable initial approach to ED management of select patients with suspected septic olecranon bursitis.
尽管缺乏强有力的临床数据来支持这一做法,并且已知抽吸存在并发症风险,但许多关于脓毒性肘突滑囊炎的指南仍建议在开始抗菌治疗前抽吸滑囊。我们的目的是描述在疑似化脓性肘突滑囊炎的急诊科患者中,不进行滑囊抽吸而单纯使用经验性抗生素治疗的相关结局。
我们对 2011 年 1 月 1 日至 2018 年 12 月 31 日期间在一家学术急诊科就诊的患有肘突滑囊炎的患者进行了回顾性观察性队列研究。通过查阅病历来评估患者的特征和急诊科就诊后 6 个月内的结局。如果患者接受了抗生素治疗,则认为肘突滑囊炎为“疑似脓毒性”。主要观察结局为复杂性与非复杂性滑囊炎缓解。非复杂性缓解定义为无需随后进行滑囊抽吸、手术或住院治疗即可缓解滑囊炎。
在研究期间,共有 264 名急诊科患者评估了 266 例肘突滑囊炎病例。患者的中位年龄为 57 岁,85%为男性。4 名(1.5%)患者在急诊科就诊时进行了滑囊抽吸,39 名(14.7%)患者住院,76 名(28.6%)未接受抗生素治疗即出院,147 名(55.3%)因疑似化脓性肘突滑囊炎而接受经验性抗生素治疗后出院。在这 147 名患者中,有 134 名患者可获得随访资料,其中 118 名(88.1%,95%置信区间 [CI] = 81.1%-92.8%)患者的滑囊炎得到非复杂性缓解,8 名(6.0%,95% CI = 2.8%-11.8%)患者随后进行了滑囊抽吸,9 名(6.7%,95% CI = 3.3%-12.7%)患者随后因住院接受抗生素治疗。
在急诊科就诊的疑似化脓性肘突滑囊炎患者中,88%接受经验性抗生素治疗而未进行抽吸的患者无需随后进行滑囊抽吸、住院或手术即可缓解。我们的研究结果表明,不进行滑囊抽吸而单纯使用经验性抗生素治疗可能是一种合理的初始治疗方法,适用于选择的疑似化脓性肘突滑囊炎患者。