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COVID-19 患者 PRES 的脑部 MRI 表现:系统评价。

Brain MRI findings in COVID-19 patients with PRES: A systematic review.

机构信息

New York Medical College, Valhalla, New York, United States of America.

Division of Neuroradiology, Department of Radiology, Westchester Medical Center, Valhalla, New York, United States of America.

出版信息

Clin Imaging. 2022 Jan;81:107-113. doi: 10.1016/j.clinimag.2021.10.003. Epub 2021 Oct 16.

DOI:10.1016/j.clinimag.2021.10.003
PMID:34700172
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8519663/
Abstract

BACKGROUND

Numerous case reports and case series have described brain Magnetic Resonance Imaging (MRI) findings in Coronavirus disease 2019 (COVID-19) patients with concurrent posterior reversible encephalopathy syndrome (PRES).

PURPOSE

We aim to compile and analyze brain MRI findings in patients with COVID-19 disease and PRES.

METHODS

PubMed and Embase were searched on April 5th, 2021 using the terms "COVID-19", "PRES", "SARS-CoV-2" for peer-reviewed publications describing brain MRI findings in patients 21 years of age or older with evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and PRES.

RESULTS

Twenty manuscripts were included in the analysis, which included descriptions of 30 patients. The average age was 57 years old. Twenty-four patients (80%) required mechanical ventilation. On brain MRI examinations, 15 (50%) and 7 (23%) of patients exhibited superimposed foci of hemorrhage and restricted diffusion respectively.

CONCLUSIONS

PRES is a potential neurological complication of COVID-19 related disease. COVID-19 patients with PRES may exhibit similar to mildly greater rates of superimposed hemorrhage compared to non-COVID-19 PRES patients.

摘要

背景

大量的病例报告和病例系列描述了合并后部可逆性脑病综合征(PRES)的 2019 年冠状病毒病(COVID-19)患者的脑部磁共振成像(MRI)表现。

目的

我们旨在汇总和分析 COVID-19 合并 PRES 患者的脑部 MRI 表现。

方法

于 2021 年 4 月 5 日,通过使用“COVID-19”“PRES”“SARS-CoV-2”等术语,在 PubMed 和 Embase 上检索同行评审文献,以描述年龄在 21 岁或以上、有严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)感染和 PRES 证据的患者的脑部 MRI 表现。

结果

有 20 篇文献被纳入分析,其中包括 30 例患者的描述。平均年龄为 57 岁。24 例(80%)患者需要机械通气。在脑部 MRI 检查中,15 例(50%)和 7 例(23%)患者分别出现了合并性出血灶和弥散受限。

结论

PRES 是 COVID-19 相关疾病的一种潜在神经系统并发症。与非 COVID-19 PRES 患者相比,COVID-19 合并 PRES 的患者可能出现更类似或略高的合并性出血发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a53/8519663/644987c97795/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a53/8519663/4acd158dc429/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a53/8519663/644987c97795/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a53/8519663/4acd158dc429/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a53/8519663/644987c97795/gr2_lrg.jpg

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Cureus. 2021 Feb 21;13(2):e13475. doi: 10.7759/cureus.13475.
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Rapid development of seizures and PRES in a COVID-19 patient.一名新冠病毒肺炎患者出现癫痫发作和可逆性后部白质脑病综合征的快速进展。
Epilepsy Behav Rep. 2021;15:100436. doi: 10.1016/j.ebr.2021.100436. Epub 2021 Mar 4.
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Case Report: Posterior Reversible Leukoencephalopathy Syndrome (PRES) as a Biologically Predictable Neurological Association in Severe COVID-19. First Reported Case From Australia and Review of Internationally Published Cases.
持续性全身支持在重症新型冠状病毒肺炎2019后迟发性缺氧性脑白质病临床病程中的意义
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Long-term cognitive dysfunction after the COVID-19 pandemic: a narrative review.新冠疫情后的长期认知功能障碍:一篇叙述性综述
Ann Med Surg (Lond). 2023 Sep 7;85(11):5504-5510. doi: 10.1097/MS9.0000000000001265. eCollection 2023 Nov.
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Posterior reversible encephalopathy syndrome (PRES) associated with SARS-CoV-2 infection in a patient under maintenance haemodialysis: a case report.与维持性血液透析患者 SARS-CoV-2 感染相关的后部可逆性脑病综合征(PRES):一例报告。
BMC Nephrol. 2023 Sep 29;24(1):286. doi: 10.1186/s12882-023-03319-7.
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Radiol Med. 2023 Oct;128(10):1217-1224. doi: 10.1007/s11547-023-01696-5. Epub 2023 Aug 25.
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