New York Medical College, Valhalla, New York, United States of America.
Division of Neuroradiology, Department of Radiology, Westchester Medical Center, Valhalla, New York, United States of America.
Clin Imaging. 2022 Jan;81:107-113. doi: 10.1016/j.clinimag.2021.10.003. Epub 2021 Oct 16.
Numerous case reports and case series have described brain Magnetic Resonance Imaging (MRI) findings in Coronavirus disease 2019 (COVID-19) patients with concurrent posterior reversible encephalopathy syndrome (PRES).
We aim to compile and analyze brain MRI findings in patients with COVID-19 disease and PRES.
PubMed and Embase were searched on April 5th, 2021 using the terms "COVID-19", "PRES", "SARS-CoV-2" for peer-reviewed publications describing brain MRI findings in patients 21 years of age or older with evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and PRES.
Twenty manuscripts were included in the analysis, which included descriptions of 30 patients. The average age was 57 years old. Twenty-four patients (80%) required mechanical ventilation. On brain MRI examinations, 15 (50%) and 7 (23%) of patients exhibited superimposed foci of hemorrhage and restricted diffusion respectively.
PRES is a potential neurological complication of COVID-19 related disease. COVID-19 patients with PRES may exhibit similar to mildly greater rates of superimposed hemorrhage compared to non-COVID-19 PRES patients.
大量的病例报告和病例系列描述了合并后部可逆性脑病综合征(PRES)的 2019 年冠状病毒病(COVID-19)患者的脑部磁共振成像(MRI)表现。
我们旨在汇总和分析 COVID-19 合并 PRES 患者的脑部 MRI 表现。
于 2021 年 4 月 5 日,通过使用“COVID-19”“PRES”“SARS-CoV-2”等术语,在 PubMed 和 Embase 上检索同行评审文献,以描述年龄在 21 岁或以上、有严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)感染和 PRES 证据的患者的脑部 MRI 表现。
有 20 篇文献被纳入分析,其中包括 30 例患者的描述。平均年龄为 57 岁。24 例(80%)患者需要机械通气。在脑部 MRI 检查中,15 例(50%)和 7 例(23%)患者分别出现了合并性出血灶和弥散受限。
PRES 是 COVID-19 相关疾病的一种潜在神经系统并发症。与非 COVID-19 PRES 患者相比,COVID-19 合并 PRES 的患者可能出现更类似或略高的合并性出血发生率。