Kaufmann R, Vranes M, Landes E
Hautarzt. 1987 Jan;38(1):31-5.
We report the case of a young man with extreme sebaceous gland hyperplasia that occurred in a diffuse pattern of aggregated papular lesions involving the entire face, neck and upper chest, together with marked seborrhoea oleosa. Oral therapy with 13-cis-retinoic acid (isotretinoin) resulted in remarkable improvement within a few weeks. Parallels from our case are drawn to familial sebaceous hyperplasia, reported by Dypre et al. in 1980 [6], and to a case of a young man with severe sebaceous gland hyperplasia and facial seborrhoea, reported by de Villez et al. in 1982. We suggest that these types of seboglandular proliferative disorders be classified as diffuse (presenile) sebaceous gland hyperplasia in contrast to the well-defined senile circumscribed variant, and that they be regarded as a separate entity.
我们报告了一例青年男性，其患有极度皮脂腺增生，表现为累及整个面部、颈部及上胸部的弥漫性聚集性丘疹样损害，并伴有明显的油性皮脂溢出。口服13 - 顺式维甲酸（异维甲酸）治疗数周内即取得显著改善。我们将本病例与1980年Dypre等人报道的家族性皮脂腺增生以及1982年de Villez等人报道的一例患有严重皮脂腺增生和面部皮脂溢出的青年男性病例进行了对比。我们建议，与明确的老年性局限性皮脂腺增生变体不同，这些类型的皮脂腺增生性疾病应归类为弥漫性（早发性）皮脂腺增生，并应将其视为一个独立的实体。
