13-顺式视黄酸对皮脂腺的作用。
The effect of 13-cis-retinoic acid on sebaceous glands.
作者信息
Strauss J S, Stewart M E, Downing D T
机构信息
Marshall Research Dermatology Research Laboratories, Department of Dermatology, University of Iowa College of Medicine, Iowa City 52242.
出版信息
Arch Dermatol. 1987 Nov;123(11):1538a-1541.
The drug, 13-cis-retinoic acid, which has been demonstrated to have a marked effect on nodulocystic acne, probably has several mechanisms of action. This article summarizes the effects on the sebaceous glands, and the accompanying changes in cutaneous lipids that result from 13-cis-retinoic acid therapy. These changes in lipid composition support the concept that linoleate may be of importance in the pathogenesis of acne.
药物13 - 顺式维甲酸已被证明对结节囊肿性痤疮有显著疗效，其作用机制可能有多种。本文总结了13 - 顺式维甲酸治疗对皮脂腺的影响以及随之而来的皮肤脂质变化。这些脂质成分的变化支持了亚油酸在痤疮发病机制中可能起重要作用的观点。
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