Waltham Petcare Science Institute, Freeby Lane, Waltham on the Wolds, Leicestershire LE14 4RT, UK.
Dis Model Mech. 2021 Oct 1;14(10). doi: 10.1242/dmm.049352. Epub 2021 Oct 27.
The 2021 Nobel Prize in Physiology or Medicine was awarded to Ardem Patapoutian and David Julius for their research on receptor channels responsible for the perception of touch and temperature. Somatosensation, an overarching sense that enables us to safely interface with the physical forces around and within us, is the fourth sensory modality to be recognized by the Nobel Committee. The story of the discovery of TRP and PIEZO channels, and subsequent investigations into their myriad roles in the perception of noxious and mild temperature, touch, pain, pressure and body position, is an archetype for how translational research into human and animal health is built on a foundation of excellence in basic science.
2021 年诺贝尔生理学或医学奖授予 Ardem Patapoutian 和 David Julius，以表彰他们在负责触觉和温度感知的受体通道研究方面的贡献。体感，即一种使我们能够安全地与周围和内部物理力相互作用的总体感觉，是诺贝尔委员会认可的第四种感觉模式。TRP 和 PIEZO 通道的发现故事，以及随后对其在有害和温和温度、触觉、疼痛、压力和身体姿势感知中的众多作用的研究，是如何将人类和动物健康的转化研究建立在基础科学卓越的基础上的一个典范。
