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长时间睡眠与老年社区居住成年人的认知脆弱有关：来自华西健康与老龄化趋势研究的结果。

Long sleep duration is associated with cognitive frailty among older community-dwelling adults: results from West China Health and Aging Trend study.

机构信息

National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, No.37 Guo Xue Xiang, Chengdu, China.

Center of Gerontology and Geriatrics, West China Hospital, Sichuan University, No.37 GuoXueXiang, Chengdu, 610041, Sichuan, China.

出版信息

BMC Geriatr. 2021 Oct 27;21(1):608. doi: 10.1186/s12877-021-02455-9.

DOI:10.1186/s12877-021-02455-9
PMID:34706663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8555015/
Abstract

OBJECTIVE

To investigate the association between sleep duration and cognitive frailty among older adults dwelling in western China.

METHODS

We used the baseline data from West China Health and Aging Trend (WCHAT) study. Sleep duration was classified as short sleep duration (< 6 h), normal sleep duration (6-8 h) and long sleep duration (≥ 9 h). Fried frailty criteria and Short Portable Mental Status Questionnaire were used to measure cognitive frailty. Multinomial logistic regression was conducted to estimate odds ratio (OR) and 95% confidence interval (CI).

RESULTS

A total of 4093 older adults (age = 67.8 ± 5.9 years, 1708 males and 2385 females) were included in the analysis. The prevalence of cognitive frailty was 11.8% among older adults in western China. Approximately 11.9% participants had short sleep duration (< 6 h); 22.2% had a long sleep duration (≥ 9 h). After adjusting for covariates, only long sleep duration was significantly associated with high risk of cognitive frailty (OR = 2.07, 95%CI = 1.60-2.68, P <  0.001) in western China older adults compared to normal sleep duration.

CONCLUSIONS

Long sleep duration was significantly related to cognitive frailty in older adults. Intervention for long sleep duration may be helpful to prevent cognitive frailty.

TRIAL REGISTRATION

Chinese Clinical Trial Registry: ChiCTR1800018895 .

摘要

目的

调查中国西部老年人睡眠时长与认知脆弱之间的关系。

方法

我们使用了中国西部健康与老龄化趋势研究（WCHAT）的基线数据。睡眠时长分为短睡眠时长（<6 小时）、正常睡眠时长（6-8 小时）和长睡眠时长（≥9 小时）。使用 Fried 衰弱标准和简易精神状态问卷评估认知脆弱。采用多分类逻辑回归估计比值比（OR）和 95%置信区间（CI）。

结果

共纳入 4093 名老年人（年龄=67.8±5.9 岁，男性 1708 人，女性 2385 人）进行分析。中国西部老年人认知脆弱的患病率为 11.8%。约 11.9%的参与者有短睡眠时长（<6 小时）；22.2%有长睡眠时长（≥9 小时）。调整混杂因素后，仅长睡眠时长与中国西部老年人认知脆弱的高风险显著相关（OR=2.07，95%CI=1.60-2.68，P<0.001），与正常睡眠时长相比。

结论

长睡眠时长与老年人的认知脆弱显著相关。干预长睡眠时长可能有助于预防认知脆弱。

试验注册

中国临床试验注册中心：ChiCTR1800018895。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba2b/8555015/a069217f2526/12877_2021_2455_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba2b/8555015/a069217f2526/12877_2021_2455_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba2b/8555015/a069217f2526/12877_2021_2455_Fig1_HTML.jpg

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