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长时和短时睡眠持续时间可通过 ADL 和抑郁的链式中介效应影响老年人的认知功能:来自 CHARLS2018 的证据。

Long and short sleep durations can affect cognitive function in older adults through the chain mediation effect of ADL and depression: evidence from CHARLS2018.

机构信息

The Second Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi, 710038, China.

Department of nursing, school of pharmacy, Changzhou University, Jiangsu, 213164, China.

出版信息

Aging Clin Exp Res. 2024 Nov 20;36(1):224. doi: 10.1007/s40520-024-02881-w.

Abstract

BACKGROUND

Both long and short sleep durations may lead to cognitive decline in the elderly individuals, though the underlying mechanisms remain unclear.

AIMS

To explore the mediating mechanism of activities of daily living and depression on different sleep durations and cognitive function in older Chinese older adults.

METHODS

This retrospective study used data from 5,899 older adults who completed the 2018 China Health and Retirement Longitudinal Surveys. We used the PROCESS macro in SPSS to determine the chain mediating effect of ADL and depression on the relationship between different sleep durations and cognitive functions.

RESULTS

(1) There were significant correlations among sleep duration, ability to perform ADL, depression, and cognitive function. (2) For sleep durations ≤ 7 h/night or > 7 h/night, ADL and depression play a chain mediating role in the relationship between sleep duration and cognitive function.

CONCLUSIONS

Shorter or longer sleep durations were associated with cognitive decline by weakening ADL and worsening depression, which suggests that medical personnel should take action to correct abnormal sleep duration in older adults. Timely treatment of ADL impairment and depression may help prevent cognitive decline.

摘要

背景

长时或短时睡眠均可能导致老年人认知能力下降,但潜在机制尚不清楚。

目的

探讨日常生活活动能力和抑郁在不同睡眠时长与认知功能关系中的中介作用。

方法

本回顾性研究使用了 2018 年中国健康与退休纵向研究中 5899 名老年人的数据。我们使用 SPSS 中的 PROCESS 宏来确定 ADL 和抑郁对不同睡眠时长与认知功能关系的链式中介效应。

结果

(1)睡眠时间、日常生活活动能力、抑郁和认知功能之间存在显著相关性。(2)对于睡眠时间≤7 小时/晚或>7 小时/晚的老年人,ADL 和抑郁在睡眠时长与认知功能之间的关系中起链式中介作用。

结论

较短或较长的睡眠时间与认知能力下降相关,这可能是通过削弱日常生活活动能力和加重抑郁所致,这提示医务人员应采取行动纠正老年人的异常睡眠时间。及时治疗日常生活活动能力受损和抑郁可能有助于预防认知能力下降。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31aa/11576880/87465327890a/40520_2024_2881_Fig1_HTML.jpg

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