Şentürk Mustafa, Çakır Murat, Yıldırım Mehmet Aykut, Kişi Ömer
Department of General Surgery, Necmettin Erbakan University Meram Medicine Faculty, Turkey.
Gastroenterol Res Pract. 2021 Oct 18;2021:8034948. doi: 10.1155/2021/8034948. eCollection 2021.
We examined cases of endoscopic stenting for palliative treatment of advanced stage esophageal cancers between January 2014 and July 2019. Age, gender, location of mass, adverse events, survival time, and stent type were evaluated. Outcomes of fully covered and uncovered self-expanding stents were compared with regard to adverse events, including stent migration and occlusion.
The mean age of the patients was 66.4 ± 1, 52 were male, and 8 were female. Patients were followed up for a mean of 133 days. The most common complication due to stenting was migration. 13 patients developed adverse events. Migration was the most common adverse event, occurring in 8 (13%) patients. Although the migration rate of fully covered stents was higher than uncovered stents, there was no statistically significant difference ( = 0.47). Stent occlusion was observed in 4 patients. In three cases, it was due to the tumor; an uncovered stent was placed again in these cases. Food-related occlusion developed in one patient. There was no statistical difference in terms of overall adverse event rate when comparing fully covered stents to uncovered stents ( = 0.68).
Endoscopic stenting is a viable palliative method with low morbidity and mortality in experienced centers. Though there are relative advantages with covered versus uncovered stents in individual cases, the overall adverse event rate is low and relatively similar.
我们研究了2014年1月至2019年7月期间接受内镜支架置入术姑息治疗晚期食管癌的病例。评估了年龄、性别、肿块位置、不良事件、生存时间和支架类型。比较了全覆膜和无覆膜自膨式支架在包括支架移位和闭塞在内的不良事件方面的结果。
患者的平均年龄为66.4±1岁,男性52例,女性8例。患者平均随访133天。支架置入术最常见的并发症是移位。13例患者出现不良事件。移位是最常见的不良事件,8例(13%)患者发生。虽然全覆膜支架的移位率高于无覆膜支架,但差异无统计学意义(P = 0.47)。4例患者观察到支架闭塞。3例是由于肿瘤;这些病例再次置入了无覆膜支架。1例患者发生了与食物相关的闭塞。比较全覆膜支架和无覆膜支架时,总体不良事件发生率无统计学差异(P = 0.68)。
在内镜经验丰富的中心,内镜支架置入术是一种可行的姑息治疗方法,发病率和死亡率较低。虽然在个别病例中,覆膜支架与无覆膜支架相比有相对优势,但总体不良事件发生率较低且较为相似。