Department of Otolaryngology-Head and Neck Surgery, Hearing Center/Hearing and Speech Science Laboratory, West China Hospital of Sichuan University, 37 Guo Xue Lane, Chengdu, People's Republic of China.
Department of Otolaryngology, Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Eur Arch Otorhinolaryngol. 2022 May;279(5):2211-2221. doi: 10.1007/s00405-021-07092-x. Epub 2021 Oct 27.
This study aimed to comprehensively review the literature and synthesize relevant data to examine the pooled prevalence of poor sleep quality (sleep impairment) and assess overall sleep quality in patients with tinnitus.
This meta-analysis systematically searched both English (PubMed, Embase, and Web of Science) and Chinese (Wanfang Data Chinese database, Veep Chinese Database, and Chinese National Knowledge Infrastructure) databases. Data extraction and quality assessment were independently performed by two authors. The pooled prevalence of sleep impairment and poor sleep quality was calculated via a random-effects model. Sub-group and sensitivity analyses were performed to explore the source of heterogeneity.
A total of seven studies were included with a total sample of 3041 tinnitus participants. The pooled prevalence of sleep impairment was 53.5% (95% confidence interval: 40.2-66.8%) and the I2 was 97.8% (Q = 7.90, p = 0.000). There were significant differences in the prevalence of poor sleep quality between males and females (39.1% vs. 44.6%, P = 0.034), between different PSQI cut-off values ≥ 7 and > 5 (53.1% vs. 53.8%, P = 0.000), and between sample sizes > 200 and ≤ 200 (54.0% vs. 52.7%, P = 0.000). In non-Asia area, the prevalence (56.6%, 95% CI: 42.6-70.5%) was lower than that in Asia areas (34.5%, 95% CI: 25.7-43.3%).
Sleep impairment is common among patients with tinnitus. Development of interventions for conditions associated with poor sleep quality should be recommended to offer a safe and efficacious solution for this population.
本研究旨在全面综述文献并综合相关数据，以评估耳鸣患者睡眠质量不佳（睡眠障碍）的总体患病率，并评估其总体睡眠质量。
本荟萃分析系统地检索了英文（PubMed、Embase 和 Web of Science）和中文（万方数据中国数据库、维普中国数据库和中国国家知识基础设施）数据库。两名作者独立进行数据提取和质量评估。采用随机效应模型计算睡眠障碍和睡眠质量差的合并患病率。进行亚组和敏感性分析以探索异质性的来源。
共纳入 7 项研究，共纳入 3041 名耳鸣参与者。睡眠障碍的合并患病率为 53.5%（95%置信区间：40.2-66.8%），I2 为 97.8%（Q=7.90，p=0.000）。男性和女性之间、PSQI 截断值≥7 与>5 之间、样本量>200 与≤200 之间的睡眠质量差患病率存在显著差异（39.1%比 44.6%，P=0.034；53.1%比 53.8%，P=0.000；54.0%比 52.7%，P=0.000）。在非亚洲地区，患病率（56.6%，95%CI：42.6-70.5%）低于亚洲地区（34.5%，95%CI：25.7-43.3%）。
睡眠障碍在耳鸣患者中较为常见。应推荐针对与睡眠质量差相关的疾病制定干预措施，为该人群提供安全有效的解决方案。
