Professor of pediatrics at the University of Utah in Salt Lake City.
AMA J Ethics. 2021 Sep 1;23(9):E685-691. doi: 10.1001/amajethics.2021.685.
An investigator's personal financial interest in technology under investigation or in the company sponsoring the research is a clear conflict of interest (COI). Such financial relationships are common, and ethical questions rightly emerge about COIs' capacity to compromise an investigator's approaches to research. This commentary on a case suggests that COI disclosure is appropriate during the process of facilitating patient-subjects' informed consent because it promotes informed decision making and motivates transparency. But COI disclosures are not always efficacious, nor are they sufficient to address the problem of research bias. This commentary argues that mitigation or elimination of COIs is a more effective strategy than disclosure.
研究者个人在研究中的技术或赞助研究的公司的经济利益是一个明显的利益冲突（COI）。这种财务关系很常见，伦理问题也确实出现了，COI 是否有能力影响研究者的研究方法。这篇关于一个案例的评论表明，在促进患者知情同意的过程中，COI 披露是合适的，因为它可以促进知情决策，并提高透明度。但是，COI 披露并不总是有效，也不足以解决研究偏见问题。本文评论认为，减轻或消除 COI 比披露更为有效。
