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新型冠状病毒时代严重高甘油三酯血症导致的急性胰腺炎:治疗性血浆置换的作用。

Acute pancreatitis due to severe hypertriglyceridemia in the COVID-19 era: The role of therapeutic plasma exchange.

机构信息

Apheresis Unit, Department of Transfusion Medicine, University Hospital of Padova, Padova, Italy.

Apheresis Unit, Department of Transfusion Medicine, University Hospital of Padova, Padova, Italy.

出版信息

Transfus Apher Sci. 2022 Feb;61(1):103292. doi: 10.1016/j.transci.2021.103292. Epub 2021 Oct 14.

Abstract

The psychosocial consequences of the COVID-19 pandemic caused multifaceted challenges in clinical and therapeutic practices. This was the case at the Therapeutic Apheresis Unit of the Padua University Hospital too. Several published reports describe the increase in alcohol and food addiction diseases. In this context, during the last months, the Padua Therapeutic Apheresis Unit treated many more patients with acute pancreatitis due to severe hypertriglyceridemia with therapeutic plasma exchange than in the previous ten years. Furthermore, retrospective cohort studies have been recently published describing the onset of acute pancreatitis during the COVID-19 infection even if, to date, there is still insufficient evidence to estabilish a direct causality. Anyway, the COVID-19 pandemic translated into changes of the overall disease prevalence scenario and therefore the Padua Therapeutic Apheresis Unit will need to reorganise its Therapeutic Apheresis activity.

摘要

COVID-19 大流行造成的心理社会后果给临床和治疗实践带来了多方面的挑战。这在帕多瓦大学医院的治疗性血液分离单位也是如此。有几项已发表的报告描述了酒精和食物成瘾疾病的增加。在这种情况下,在过去的几个月里,与前十年相比,帕多瓦治疗性血液分离单位用治疗性血浆置换治疗了更多因严重高甘油三酯血症导致的急性胰腺炎患者。此外,最近发表了回顾性队列研究,描述了 COVID-19 感染期间急性胰腺炎的发作,尽管迄今为止,仍然没有足够的证据确定直接的因果关系。无论如何,COVID-19 大流行改变了整体疾病流行情况,因此帕多瓦治疗性血液分离单位将需要重新组织其治疗性血液分离活动。

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Severe hypertriglyceridemia-related acute pancreatitis.严重高甘油三酯血症相关性急性胰腺炎
Ther Apher Dial. 2013 Apr;17(2):130-7. doi: 10.1111/1744-9987.12008. Epub 2013 Feb 28.

本文引用的文献

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COVID-19 presenting as acute pancreatitis.COVID-19 表现为急性胰腺炎。
Pancreatology. 2020 Jul;20(5):1026-1027. doi: 10.1016/j.pan.2020.05.003. Epub 2020 May 8.
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Pancreatic Injury Patterns in Patients With Coronavirus Disease 19 Pneumonia.新型冠状病毒肺炎患者的胰腺损伤模式
Gastroenterology. 2020 Jul;159(1):367-370. doi: 10.1053/j.gastro.2020.03.055. Epub 2020 Apr 1.

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