Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Hubei Province for the Clinical Medicine Research Center of Hepatic Surgery, Wuhan, Hubei, China.
Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Hubei Province for the Clinical Medicine Research Center of Hepatic Surgery, Wuhan, Hubei, China.
Clin Gastroenterol Hepatol. 2020 Aug;18(9):2128-2130.e2. doi: 10.1016/j.cgh.2020.04.040. Epub 2020 Apr 22.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus that causes coronavirus disease 2019 (COVID-19) in human beings, has caused a serious public health issue. Attention to pancreatic injury is lacking, which may impact patients' prognosis. In this study, we explored the expression and distribution of angiotensin-converting enzyme 2 (ACE2), the receptor of SARS-CoV-2, in the pancreas. Combined with clinical data, we showed that pancreatic injury can occur in some COVID-19 patients.
严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)是一种新型冠状病毒,可导致人类 2019 年冠状病毒病(COVID-19),已造成严重的公共卫生问题。目前对胰腺损伤的关注度不足,这可能影响患者的预后。本研究探讨了血管紧张素转换酶 2(ACE2),即 SARS-CoV-2 的受体,在胰腺中的表达和分布。结合临床资料,我们表明一些 COVID-19 患者可发生胰腺损伤。