Monlux Katerina D, Pollard Joy S, Bujanda Rodriguez Arlette Y, Hall Scott S
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA; and.
Behavior Change Institute, Oakland, CA.
J Dev Behav Pediatr. 2022 May 1;43(4):e237-e245. doi: 10.1097/DBP.0000000000001019. Epub 2021 Oct 27.
Boys with fragile X syndrome (FXS) are at increased risk for exhibiting aggression and self-injury that can be extremely disruptive to families. Few studies, however, have examined the extent to which social-environmental factors can influence these behaviors, particularly in home settings.
Caregivers of 32 boys with FXS, aged 3 to 10 years, were coached by a board-certified behavior analyst to implement a functional analysis (FA) with their child in their home over 2 days. The functions identified in the FAs were validated by behavioral interventions conducted through telehealth over 12 weeks.
Social functions for aggression and self-injury were identified in 29 (90.6%) cases, with the most common functions identified being escape from demands/transitions and/or tangible reinforcement. Subsequent function-based behavioral interventions (i.e., functional communication training) implemented for 22 cases by telehealth resulted in decreased rates of aggression and self-injury by 74% to 100%.
These data underscore the significant impact that social-environmental factors can have on the development and maintenance of aggression and self-injury in FXS. Conducting early home-based behavioral interventions designed to increase functional communication skills may therefore be an effective solution for the treatment of aggression and self-injury in FXS in the long term.
患有脆性X综合征(FXS)的男孩表现出攻击行为和自我伤害行为的风险增加,这可能会给家庭带来极大的困扰。然而,很少有研究探讨社会环境因素在多大程度上会影响这些行为,尤其是在家庭环境中。
32名年龄在3至10岁的患有FXS的男孩的照顾者,在一名获得董事会认证的行为分析师的指导下,在两天内于家中对他们的孩子进行功能分析(FA)。通过远程医疗在12周内进行的行为干预对功能分析中确定的功能进行了验证。
在29例(90.6%)中确定了攻击行为和自我伤害行为的社会功能,最常见的功能是逃避要求/过渡和/或物质强化。随后通过远程医疗对22例实施的基于功能的行为干预(即功能性沟通训练)使攻击行为和自我伤害行为的发生率降低了74%至100%。
这些数据强调了社会环境因素对FXS中攻击行为和自我伤害行为的发展和维持可能产生的重大影响。因此,开展旨在提高功能性沟通技能的早期家庭行为干预可能是长期治疗FXS中攻击行为和自我伤害行为的有效解决方案。