Limon J, Dal Cin P, Kakati S, Huben R P, Sandberg A A
Cancer Genet Cytogenet. 1987 Jun;26(2):271-7. doi: 10.1016/0165-4608(87)90061-6.
Cytogenetic analysis of a primary adrenocortical carcinoma revealed clonal rearrangements of several autosomes and sex chromosomes. In all metaphases the following marker chromosomes were present: 4p+,t(3;12)(p14;p13),14q+, t(15;20)(p11;q11), t(5;18) (p13.3;p11.2), psu dic(18)t(18.3)(p11.39;p12), and psu dic(20)t(20;9)(q11.2;p11). The results are discussed in relation to the cytogenetic findings in other solid tumors, especially of the kidney.
对一例原发性肾上腺皮质癌进行细胞遗传学分析,发现几条常染色体和性染色体存在克隆性重排。在所有中期相中,均出现以下标记染色体:4p+、t(3;12)(p14;p13)、14q+、t(15;20)(p11;q11)、t(5;18)(p13.3;p11.2)、psu dic(18)t(18;3)(p11.39;p12)以及psu dic(20)t(20;9)(q11.2;p11)。结合其他实体瘤尤其是肾癌的细胞遗传学研究结果,对这些结果进行了讨论。