肾上腺皮质癌中的4号与11号染色体易位t(4;11)(q35;p13)
Translocation t(4;11)(q35;p13) in an adrenocortical carcinoma.
作者信息
Limon J, Dal Cin P, Gaeta J, Sandberg A A
出版信息
Cancer Genet Cytogenet. 1987 Oct;28(2):343-8. doi: 10.1016/0165-4608(87)90221-4.
PMID:3476190
Abstract
Chromosome studies were performed on an adrenocortical carcinoma extending into the kidney. The following karyotype was present in all metaphases: 46,XX,t(4;11)(q35;p13). Two metaphases with an additional del(1)(q23) were found. The results are briefly discussed in relation to specific karyotypic changes in cancer, in general, and to those of adrenocortical tumors, in particular.
摘要
对一例延伸至肾脏的肾上腺皮质癌进行了染色体研究。所有中期细胞均呈现以下核型：46,XX,t(4;11)(q35;p13)。发现两个中期细胞带有额外的del(1)(q23)。本文简要讨论了这些结果，涉及癌症中一般的特定核型变化，特别是肾上腺皮质肿瘤的核型变化。
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