Laboratory of Neuropsychophysiology, Faculty of Psychology and Education Sciences, University of Porto, Portugal.
Laboratory of Neuropsychophysiology, Faculty of Psychology and Education Sciences, University of Porto, Portugal.
Neurosci Biobehav Rev. 2021 Dec;131:1243-1263. doi: 10.1016/j.neubiorev.2021.10.030. Epub 2021 Oct 29.
The effect of pathological aging on economic decision-making is a topic of major relevance as impairments in this domain place older adults at increased risk for financial abuse. This review aims to characterize decision-making across the continuum that goes from healthy aging to Alzheimer's Dementia. We included 42 studies comparing patients with Mild Cognitive Impairment (MCI) and healthy older adults, patients with Alzheimer's Disease (AD) and healthy older adults, and patients with MCI and patients with AD. Substantial evidence emerged suggesting that both MCI as AD affect economic decision-making. However, a non-negligible number of behavioural tasks failed to find significant differences between patients and controls, and no differences were reported between patients with MCI and AD. On the contrary, measures of financial capacity reached more robust findings, showing that healthy older adults had better performance than patients, while MCI patients showed better performance than AD patients. This review presents the main conclusions that may be drawn from significant findings, as well as the hypotheses and recommendations for future research.
病理性衰老对经济决策的影响是一个重大问题，因为在这一领域的损伤会使老年人面临更高的财务滥用风险。本综述旨在描述从健康衰老到阿尔茨海默病的连续体上的决策。我们纳入了 42 项研究，这些研究比较了轻度认知障碍（MCI）患者和健康老年人、阿尔茨海默病（AD）患者和健康老年人，以及 MCI 患者和 AD 患者。大量证据表明，MCI 和 AD 都会影响经济决策。然而，相当数量的行为任务没有发现患者和对照组之间的显著差异，也没有报告 MCI 患者和 AD 患者之间的差异。相反，财务能力的衡量标准得出了更有力的结论，表明健康老年人的表现优于患者，而 MCI 患者的表现优于 AD 患者。本综述介绍了从显著发现中可以得出的主要结论，以及未来研究的假设和建议。
