University of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, Zátišíi 728/II, 389 25, Vodňany, Czech Republic.
University of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, Zátišíi 728/II, 389 25, Vodňany, Czech Republic.
Fish Shellfish Immunol. 2021 Dec;119:575-577. doi: 10.1016/j.fsi.2021.10.035. Epub 2021 Oct 26.
Juvenile common carp Cyprinus carpio L. (5.52 ± 1.66 cm, TL) were fed on four diets containing either beta-glucan (MacroGard, 1 g kg -1), nucleotides (Optimûn, 0.2 g kg - 1), chitosan (deacetylated chitin ≥75% shrimp shells, 10 g kg -1) or a basal control diet for 35 days to test whether these so-called "immunostimulants" could affect eye fluke Diplostomum spp. infection success. The immunostimulants diets reduced the number of eye fluke infecting the eyes of C. carpio, with significantly higher infections in the control diet (4.78 ± 1.27) compared with the chitosan (2.08 ± 0.87), nucleotide (2.98 ± 1.01), and beta-glucan (1.41 ± 0.79) diets. To our knowledge, this is the first study to provide evidence that beta-glucan, nucleotides, and chitosan diets can aid against a Diplostomum infection and provides valuable preliminary knowledge on the use of immunostimulants to ameliorate parasitic infections.
将 5.52±1.66cm（TL）的幼鲤（Cyprinus carpio L.）分别投喂含有β-葡聚糖（MacroGard，1g/kg）、核苷酸（Optimûn，0.2g/kg）、壳聚糖（脱乙酰壳多糖≥75%虾壳，10g/kg）或基础对照饲料的四种饲料 35 天，以测试这些所谓的“免疫增强剂”是否会影响眼吸虫（Diplostomum spp.）的感染成功率。免疫增强剂饲料减少了感染鲤眼的眼吸虫数量，与壳聚糖（2.08±0.87）、核苷酸（2.98±1.01）和β-葡聚糖（1.41±0.79）饲料相比，对照组饲料的感染率显著更高（4.78±1.27）。据我们所知，这是第一项提供证据表明β-葡聚糖、核苷酸和壳聚糖饲料可以帮助抵御眼吸虫感染的研究，并为使用免疫增强剂来减轻寄生虫感染提供了有价值的初步知识。
