Binzhou Medical University, Yantai, Shandong, China.
Department of Urology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, NO. 20 East Yuhuangding Road, Yantai, 264000, Shandong, China.
BMC Nephrol. 2021 Oct 29;22(1):356. doi: 10.1186/s12882-021-02565-x.
Xanthogranulomatous pyelonephritis (XGP) is a rare and severe chronic inflammatory disease of the renal parenchyma, which is most commonly associated with super-infections by bacteria such as E. coli, Proteus mirabilis, and occasionally Pseudomonas species.
Herein, we present a rare case of a patient with XGP infected with Providencia stuartii. Initially, the patient refused nephrectomy and underwent holmium laser lithotripsy and right ureteral stenting, followed by meropenem treatment of 7 days. Relapse occurred in the third month after discharge from the hospital, due to which she underwent a radical nephrectomy.
The diagnosis of XGP is confirmed by histopathology. The standard treatment for XGP is antibiotic therapy and radical nephrectomy, but partial nephrectomy may be appropriate in select cases.
黄肉芽肿性肾盂肾炎(XGP)是一种罕见且严重的肾脏实质慢性炎症性疾病,最常与大肠埃希菌、奇异变形杆菌等细菌的超级感染有关,偶尔也与假单胞菌属有关。
本文报告了一例罕见的感染普罗威登斯菌属的 XGP 患者。最初,该患者拒绝肾切除术,并接受钬激光碎石术和右输尿管支架置入术,随后接受美罗培南治疗 7 天。出院后第三个月复发,因此接受根治性肾切除术。
XGP 的诊断通过组织病理学确认。XGP 的标准治疗方法是抗生素治疗和根治性肾切除术,但在某些情况下部分肾切除术可能是合适的。