儿科脑的质子和多核光谱学。

Proton and Multinuclear Spectroscopy of the Pediatric Brain.

机构信息

Department of Radiology, Children's National Hospital, 111 Michigan Avenue NW, Washington, DC 20010, USA; Prenatal Pediatrics Institute, Children's National Hospital, Washington, DC, USA; The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.

Department of Radiology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, 450 Sunset Boulevard, Los Angeles, CA 90027, USA; Rudi Schulte Research Institute, Santa Barbara, CA, USA.

出版信息

Magn Reson Imaging Clin N Am. 2021 Nov;29(4):543-555. doi: 10.1016/j.mric.2021.06.006.

DOI:10.1016/j.mric.2021.06.006

PMID:34717844

Abstract

Magnetic resonance spectroscopy (MRS) is a valuable adjunct to structural brain imaging. State-of-the-art MRS has benefited greatly from recent technical advancements. Neurometabolic alterations in pediatric brain diseases have implications for diagnosis, prognosis, and therapy. Herein, the authors discuss MRS technical considerations and applications in the setting of various pediatric disease processes including tumors, metabolic diseases, hypoxic/ischemic encephalopathy/stroke, epilepsy, demyelinating disease, and infection.

摘要

磁共振波谱（MRS）是结构脑成像的重要辅助手段。最先进的 MRS 技术得益于最近的技术进步而受益匪浅。儿科脑疾病中的神经代谢改变对诊断、预后和治疗具有重要意义。本文作者讨论了 MRS 技术在各种儿科疾病过程中的考虑因素和应用，包括肿瘤、代谢疾病、缺氧/缺血性脑病/中风、癫痫、脱髓鞘疾病和感染。