Shi Yan, Zhou Ling, Yan Enshi, Yang Ling, Yang Chun, Liu Cunming
Department of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital of Nanjing Medical University, 210029 Nanjing, Jiangsu, China.
Department of Anesthesiology, Affiliated Stomatological Hospital, Nanjing Medical University, 210029 Nanjing, Jiangsu, China.
Front Biosci (Landmark Ed). 2021 Oct 30;26(10):882-894. doi: 10.52586/4995.
Sarcopenia is the age-related loss of skeletal muscle mass, accompanied by reduced muscle strength or physical function. As the global population continues to age, the prevalence of sarcopenia is gradually increasing. It is conceivable that an increasing number of patients with sarcopenia will be scheduled for surgery and anesthesia in the near future. The complex pathogenesis and clinical features of sarcopenia have brought huge challenges to perioperative management, especially in clinical anesthesia. However, there are currently neither guidelines nor expert consensus on the perioperative management of patients with sarcopenia. In this review, we summarize and elaborate on the pathogenesis, diagnosis, and perioperative precautions of sarcopenia, thereby providing information on the perioperative and anesthestic management of patients with sarcopenia.
肌肉减少症是与年龄相关的骨骼肌质量流失,并伴有肌肉力量或身体功能下降。随着全球人口持续老龄化,肌肉减少症的患病率逐渐上升。可以想象,在不久的将来,越来越多的肌肉减少症患者将接受手术和麻醉。肌肉减少症复杂的发病机制和临床特征给围手术期管理带来了巨大挑战,尤其是在临床麻醉方面。然而,目前对于肌肉减少症患者的围手术期管理既没有指南也没有专家共识。在这篇综述中,我们总结并详细阐述了肌肉减少症的发病机制、诊断及围手术期注意事项,从而为肌肉减少症患者的围手术期及麻醉管理提供信息。