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右美托咪定治疗大麻戒断综合征延迟高峰症状:一例报告

Dexmedetomidine for Treatment of Delayed Peak Symptoms of Cannabis Withdrawal Syndrome: A Case Report.

作者信息

MacCamy Katie, Hu Daniel

机构信息

College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA, USA.

Providence St. Peter Hospital, Olympia, WA, USA.

出版信息

Hosp Pharm. 2021 Oct;56(5):462-465. doi: 10.1177/0018578720919025. Epub 2020 May 13.

Abstract

Cannabis withdrawal syndrome (CWS) is characterized by irritability, sleep disorders, and physical discomfort that typically peaks within 7 days of cessation. A patient with a 30-year history of heavy cannabis developed prolonged symptoms of CWS that peaked at greater than 40 days after cessation, who was successfully managed with dexmedetomidine. This case report documents an unusual case of significantly delayed CWS peak in symptoms, as well as the novel use of dexmedetomidine for inpatient management of CWS.

摘要

大麻戒断综合征(CWS)的特征是易怒、睡眠障碍和身体不适,这些症状通常在停止使用大麻后7天内达到峰值。一名有30年大量使用大麻史的患者出现了CWS的延长症状,在停止使用大麻后40多天达到峰值,该患者通过右美托咪定成功得到治疗。本病例报告记录了一例症状峰值明显延迟的CWS罕见病例,以及右美托咪定在CWS住院治疗中的新应用。

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本文引用的文献

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The cannabis withdrawal syndrome: current insights.大麻戒断综合征:当前见解
Subst Abuse Rehabil. 2017 Apr 27;8:9-37. doi: 10.2147/SAR.S109576. eCollection 2017.
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Use of dexmedetomidine to treat delirium primarily caused by cannabis.使用右美托咪定治疗主要由大麻引起的谵妄。
Am J Emerg Med. 2017 Mar;35(3):524.e1-524.e2. doi: 10.1016/j.ajem.2016.10.027. Epub 2016 Oct 11.
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The cannabis withdrawal syndrome.大麻戒断综合征。
Curr Opin Psychiatry. 2006 May;19(3):233-8. doi: 10.1097/01.yco.0000218592.00689.e5.

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