副肿瘤性眼肌麻痹作为小儿多形性胶质母细胞瘤的首发症状：一例报告
Paraneoplastic Ophthalmoplegia as the Presenting Sign of Paediatric Glioblastoma Multiforme: A Case Report.
作者信息
Dhoot Arjan S, Just Caroline, Bursztyn Lulu Lcd
机构信息
Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Department of Clinical Neurological Sciences, Western University Schulich School of Medicine and Dentistry, London, Ontario, Canada.
出版信息
Neuroophthalmology. 2020 Sep 22;45(6):397-402. doi: 10.1080/01658107.2020.1817098. eCollection 2021.
Abstract
Glioblastoma multiforme (GBM) is an aggressive glioma that is infrequently diagnosed in the paediatric population. GBM and other primary brain tumours have rarely been associated with paraneoplastic syndromes. We report an unusual case of an 8-year-old boy presenting with an inability to abduct his left eye and almost complete ophthalmoplegia of his right eye, prior to any radiological evidence of GBM. This is the first documented case of paediatric GBM presenting with bilateral asymmetric ophthalmoplegia.
摘要
多形性胶质母细胞瘤（GBM）是一种侵袭性胶质瘤，在儿科人群中很少被诊断出来。GBM和其他原发性脑肿瘤很少与副肿瘤综合征相关。我们报告了一例罕见病例，一名8岁男孩在出现GBM的任何影像学证据之前，表现为左眼外展不能和右眼几乎完全性眼肌麻痹。这是首例有文献记载的以双侧不对称性眼肌麻痹为表现的儿童GBM病例。
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