Sharifi Mohammad, Tafaghodi Yousefi Bahar
Eye Research Center, Mashhad University of Medical Science, Mashhad, Iran.
Case Rep Oncol. 2021 Sep 14;14(3):1304-1309. doi: 10.1159/000518682. eCollection 2021 Sep-Dec.
Benign fibrous histiocytoma of the para nasal sinus is a rare tumor of this region which originates from mesenchymal cells. A 9-year-old girl presented with gradually enlarging mass above the medial canthus over 3 months. Orbital computerized tomography scan showed a round well-differentiated homogeneous mass in the anterior ethmoidal sinus. Histology and immunohistochemistry analysis after excision revealed proliferation of spindle-shaped fibroblasts in storiform pattern and histiocytes without mitosis and anaplasia. After 9 months from surgical excision, recurrence occurred which resulted in total excision again. This is the first reported case of benign fibrous histiocytoma involving the ethmoid sinus in Iranian people. Rare sinus tumor should be considered in the differential diagnosis of sinus tumors.
鼻窦良性纤维组织细胞瘤是该区域一种罕见的肿瘤,起源于间充质细胞。一名9岁女孩在3个月内出现内眦上方逐渐增大的肿块。眼眶计算机断层扫描显示筛窦前部有一个圆形、分化良好的均匀肿块。切除术后的组织学和免疫组织化学分析显示,梭形成纤维细胞呈席纹状增生,组织细胞无有丝分裂和间变。手术切除9个月后复发,再次进行了全切。这是伊朗人群中首例报道的累及筛窦的良性纤维组织细胞瘤。鼻窦肿瘤的鉴别诊断应考虑罕见的鼻窦肿瘤。