弥漫性大B细胞淋巴瘤R-CHOP化疗期间因感染引起的复发性发热：病例报告及文献复习
Recurrent Fever due to Infection during R-CHOP Chemotherapy in Diffuse Large B-Cell Lymphoma: Case Report and Literature Review.
作者信息
Takenaka Kei, Sugimoto Takeshi, Kawamura Kohei, Fukumoto Takeshi, Onuma Kenichiro, Naito Takuya, Oka Masahiro
机构信息
Department of Hematology, Kita-Harima Medical Center, Ono City, Japan.
Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.
出版信息
Case Rep Oncol. 2021 Sep 16;14(3):1315-1322. doi: 10.1159/000518685. eCollection 2021 Sep-Dec.
Fever due to bacteremia under chemotherapy has not been widely recognized among clinicians. We experienced a 72-year-old man with diffuse large B-cell lymphoma, who was complicated with bacteremia-induced fever under R-CHOP chemotherapy. We summarized 6 cases including ours, suggesting that fever without neutropenia developing around day 6 from starting chemotherapy is a possible symptom caused by bacteremia. We should discriminate fever due to bacteremia if fever emerged before myelosuppression in the course of chemotherapy.
化疗期间由菌血症引起的发热在临床医生中尚未得到广泛认识。我们遇到一名72岁的弥漫性大B细胞淋巴瘤男性患者，在接受R-CHOP化疗时并发了菌血症引起的发热。我们总结了包括我们的病例在内的6例病例，提示在化疗开始后第6天左右出现的无中性粒细胞减少的发热可能是菌血症引起的症状。如果在化疗过程中骨髓抑制之前出现发热，我们应该鉴别是否为菌血症引起的发热。
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