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一名成人继发于K1型脑膜炎的双侧半球皮质梗死

Bihemispheric Cortical Infarcts in an Adult Secondary to K1 Meningitis.

作者信息

Gogia Bhanu, Young Angela L, O'Brien Barbara J, Okhuysen Pablo C, Kumar Vinodh A

机构信息

Department of Neurology, University of Texas Medical Branch, Galveston, Texas, USA.

Department of Neuroradiology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

出版信息

Case Rep Neurol. 2021 Aug 24;13(2):572-577. doi: 10.1159/000518312. eCollection 2021 May-Aug.

DOI:10.1159/000518312
PMID:34720964
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8460961/
Abstract

Cerebral ischemia is a known complication of meningitis. Most meningitis-induced infarcts have been reported in the neonatal and pediatric population. To the best of our knowledge, there have been no previous reports describing bilateral cortical infarcts in an adult secondary to a K1 strain of meningitis, and herein we report a case in a 25-year-old female. The challenge in treating this patient was determining the duration of systemic antibiotic treatment and whether or not to use steroids. This study demonstrates the necessity of early diagnosis and treatment of meningitis to prevent neurological complications, including stroke.

摘要

脑缺血是脑膜炎已知的并发症。大多数脑膜炎所致梗死见于新生儿和儿童群体。据我们所知,此前尚无关于成人因K1型脑膜炎继发双侧皮质梗死的报道,在此我们报告一例25岁女性患者。治疗该患者的挑战在于确定全身抗生素治疗的持续时间以及是否使用类固醇。本研究表明早期诊断和治疗脑膜炎对于预防包括中风在内的神经并发症的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d46/8460961/9ff1d297d7c5/crn-0013-0572-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d46/8460961/5dd285185adb/crn-0013-0572-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d46/8460961/9ff1d297d7c5/crn-0013-0572-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d46/8460961/5dd285185adb/crn-0013-0572-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d46/8460961/9ff1d297d7c5/crn-0013-0572-g02.jpg

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本文引用的文献

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Front Cell Infect Microbiol. 2020 Nov 23;10:592017. doi: 10.3389/fcimb.2020.592017. eCollection 2020.
2
Lacunar Stroke in Cryptococcal Meningitis: Clinical and Radiographic Features.隐球菌性脑膜炎中的腔隙性卒中:临床及影像学特征
J Stroke Cerebrovasc Dis. 2019 Jun;28(6):1767-1772. doi: 10.1016/j.jstrokecerebrovasdis.2018.12.043. Epub 2019 Jan 14.
3
Thrombolytic Therapy in Severe Cardioembolic Stroke After Reversal of Dabigatran with Idarucizumab: Case Report and Literature Review.
达比加群用依达赛珠单抗逆转后在严重心源性栓塞性卒中中的溶栓治疗:病例报告及文献综述
J Stroke Cerebrovasc Dis. 2018 Jul;27(7):e128-e131. doi: 10.1016/j.jstrokecerebrovasdis.2018.02.025. Epub 2018 Mar 16.
4
Cardioembolic Stroke.心源性栓塞性卒中
Circ Res. 2017 Feb 3;120(3):514-526. doi: 10.1161/CIRCRESAHA.116.308407.
5
Cerebral infarction pattern in tuberculous meningitis.结核性脑膜炎的脑梗死模式。
Sci Rep. 2016 Dec 13;6:38802. doi: 10.1038/srep38802.
6
Human Meningitis-Associated Escherichia coli.人类脑膜炎相关大肠杆菌
EcoSal Plus. 2016 May;7(1). doi: 10.1128/ecosalplus.ESP-0015-2015.
7
Value of brain MRI in infective endocarditis: a narrative literature review.脑磁共振成像在感染性心内膜炎中的价值:一篇叙述性文献综述
Eur J Clin Microbiol Infect Dis. 2016 Feb;35(2):159-68. doi: 10.1007/s10096-015-2523-6. Epub 2015 Nov 19.
8
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Clin Infect Dis. 2004 Nov 1;39(9):1267-84. doi: 10.1086/425368. Epub 2004 Oct 6.
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Steroids in adults with acute bacterial meningitis: a systematic review.成人急性细菌性脑膜炎中使用类固醇:一项系统评价。
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