Ooi Suyi, Raviskanthan Subahari, Campbell Bruce C V, Hutton Elspeth J, Mitchell Peter J, Cloud Geoffrey C
Department of Neurology, Royal Melbourne Hospital, Melbourne, VIC, Australia.
Department of Neurology, Monash Health, Melbourne, VIC, Australia.
Front Neurol. 2021 Oct 13;12:746099. doi: 10.3389/fneur.2021.746099. eCollection 2021.
The diagnosis of fat embolism syndrome typically involves neurological, respiratory and dermatological manifestations of microvascular occlusion 24-72 h after a precipitating event. However, fat embolism causing cerebral large vessel occlusion strokes and their sequelae have rarely been reported in the literature. This case series reports three patients with fat emboli post operatively causing cerebral large vessel occlusions, as well as a review of the literature to identify differences in clinical presentations and outcomes in stroke secondary to fat emboli causing large vessel occlusions compared to those with fat embolism syndrome.
脂肪栓塞综合征的诊断通常涉及在诱发事件发生后24 - 72小时出现的微血管阻塞的神经、呼吸和皮肤表现。然而,脂肪栓塞导致大脑大血管闭塞性中风及其后遗症在文献中鲜有报道。本病例系列报告了3例术后脂肪栓子导致大脑大血管闭塞的患者,并对文献进行综述,以确定与脂肪栓塞综合征相比,由脂肪栓子导致大血管闭塞的中风在临床表现和预后方面的差异。