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一名接受急性淋巴细胞白血病诱导化疗的儿童出现危及生命的隐孢子虫腹泻。

Life-Threatening Cryptosporidium Diarrhea in a Child on Induction Chemotherapy for Acute Lymphoblastic Leukemia.

作者信息

Bakliwal Anamika, Nath Uttam Kumar, Mohanty Aroop, Gupta Pratima

机构信息

Medical Oncology and Haematology, All India Institute of Medical Science Rishikesh, Rishikesh, IND.

Clinical Microbiology, All India Institute of Medical Science Gorakhpur, Gorakhpur, IND.

出版信息

Cureus. 2021 Sep 28;13(9):e18340. doi: 10.7759/cureus.18340. eCollection 2021 Sep.

DOI:10.7759/cureus.18340
PMID:34722091
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8551933/
Abstract

Cryptosporidium infection is usually self-limiting but can be life-threatening in immunocompromised patients. It has emerged as an important cause of diarrhea in such patients worldwide. In this report, we describe a case of Cryptosporidium diarrhea in a child on induction therapy for acute lymphoblastic leukemia (ALL); timely diagnosis using multiplex polymerase chain reaction (PCR) led to definitive treatment and a favorable outcome in our patient.

摘要

隐孢子虫感染通常为自限性,但在免疫功能低下的患者中可能危及生命。在全球范围内,它已成为此类患者腹泻的重要原因。在本报告中,我们描述了一例急性淋巴细胞白血病(ALL)诱导治疗期间的儿童隐孢子虫腹泻病例;使用多重聚合酶链反应(PCR)进行及时诊断,使我们的患者得到了明确的治疗并取得了良好的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c21/8551933/84cea342f2d7/cureus-0013-00000018340-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c21/8551933/84cea342f2d7/cureus-0013-00000018340-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c21/8551933/84cea342f2d7/cureus-0013-00000018340-i01.jpg

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Life-Threatening Cryptosporidium Diarrhea in a Child on Induction Chemotherapy for Acute Lymphoblastic Leukemia.一名接受急性淋巴细胞白血病诱导化疗的儿童出现危及生命的隐孢子虫腹泻。
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[Chronic diarrhea due to Cryptosporidium in an immunocompetent subject].[免疫功能正常个体中由隐孢子虫引起的慢性腹泻]
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引用本文的文献

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本文引用的文献

1
Comparison of current methods used to detect Cryptosporidium oocysts in stools.比较目前用于检测粪便中隐孢子虫卵囊的方法。
Int J Hyg Environ Health. 2018 Jun;221(5):743-763. doi: 10.1016/j.ijheh.2018.04.006. Epub 2018 Apr 21.
2
Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study.发展中国家婴幼儿腹泻疾病负担和病因学(全球肠道发病和生存研究,GEMS):一项前瞻性、病例对照研究。
Lancet. 2013 Jul 20;382(9888):209-22. doi: 10.1016/S0140-6736(13)60844-2. Epub 2013 May 14.
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Looking for Cryptosporidium: the application of advances in detection and diagnosis.
寻找隐孢子虫:检测和诊断技术的应用进展。
Trends Parasitol. 2013 May;29(5):237-51. doi: 10.1016/j.pt.2013.03.001. Epub 2013 Apr 6.
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Azithromycin as treatment for cryptosporidiosis in human immunodeficiency virus disease.阿奇霉素作为人类免疫缺陷病毒病中隐孢子虫病的治疗药物。
J Postgrad Med. 2002 Jul-Sep;48(3):179-81.
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Diarrhoea due to Cryptosporidium in acute lymphoblastic leukemia.急性淋巴细胞白血病患者因隐孢子虫引起的腹泻
Arch Dis Child. 1985 Jan;60(1):60-2. doi: 10.1136/adc.60.1.60.