Khalilian Mohammad Reza, Mollatayefeh Abbas, Tahouri Tahmineh, Mahdavi Arash, Dalirani Reza
Department of Pediatrics, School of Medicine, Shahid Modarres cardiovascular Medical and Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Pediatrics, School of Medicine, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Qatar Med J. 2021 Oct 19;2021(3):54. doi: 10.5339/qmj.2021.54. eCollection 2021.
ackground and aims: Congenital heart disease (CHD) is described as an abnormality in the heart structure or intra-thoracic great vessels that leads to functional problems. Since most of these disorders require medical and surgical interventions identifying concomitant disorders such as renal and urinary tract abnormalities is of great importance in the management of these patients. The present study aimed to investigate the relative frequency of abnormal kidney and urinary tract findings in abdominal cineangiography during cardiac catheterization of patients with CHD in Shahid Modarres Cardiovascular Medical and Research Center.
The present study was performed prospectively on 545 patients aged < 18 years with CHD who underwent cardiac catheterization and concurrent abdominal cineangiography in Shahid Modarres Cardiovascular, Medical and Research Center, Tehran, Iran during a three-year period. The required data were extracted using a researcher-made questionnaire from patients' electronic medical files.
Of a total of 545 patients in this study, 26 had both CHD and renal or urinary tract malformation. Patent ductus arteriosus was the most common CHD in patients with renal or urinary tract malformations (odds ratio: 1.2, 95%, CI: 2.25-11.63). In this study, the most common renal and urinary malformations among CHD patients was partial duplication of the kidney followed by Ureteropelvic Junction Obstruction.
Since the prevalence of renal and urinary tract malformations is higher in CHD patients, performance of concurrent abdominal cineangiography during cardiac catheterization may lead to early diagnosis and treatment as well as better pre- and post-operative management of patients.
背景与目的:先天性心脏病(CHD)被描述为心脏结构或胸内大血管的异常,可导致功能问题。由于这些疾病大多需要药物和手术干预,因此识别诸如肾脏和泌尿系统异常等伴随疾病对于这些患者的管理至关重要。本研究旨在调查在沙希德·莫达雷斯心血管医学与研究中心接受CHD患者心脏导管插入术期间,腹部血管造影中肾脏和泌尿系统异常发现的相对频率。
本研究前瞻性地对545名年龄小于18岁的CHD患者进行,这些患者在三年期间于伊朗德黑兰的沙希德·莫达雷斯心血管医学与研究中心接受了心脏导管插入术及同期腹部血管造影。所需数据通过研究者自制的问卷从患者的电子病历中提取。
在本研究的545名患者中,26名同时患有CHD和肾脏或泌尿系统畸形。动脉导管未闭是患有肾脏或泌尿系统畸形患者中最常见的CHD(优势比:1.2,95%置信区间:2.25 - 11.63)。在本研究中,CHD患者中最常见的肾脏和泌尿系统畸形是肾脏部分重复,其次是输尿管肾盂连接处梗阻。
由于CHD患者中肾脏和泌尿系统畸形的患病率较高,在心脏导管插入术期间进行同期腹部血管造影可能有助于早期诊断和治疗,以及对患者进行更好的术前和术后管理。