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含酒精洗手液——成分、正确使用方法及注意事项。

Alcohol-based hand sanitizer - composition, proper use and precautions.

作者信息

Saha Tushar, Khadka Prakash, Das Shyamal C

机构信息

MPharm, University of Otago School of Pharmacy, Adams Building, 18 Frederick Street, Dunedin 9016, New Zealand.

PhD, University of Otago School of Pharmacy, Adams Building, 18 Frederick Street, Dunedin 9016, New Zealand.

出版信息

Germs. 2021 Sep 29;11(3):408-417. doi: 10.18683/germs.2021.1278. eCollection 2021 Sep.

Abstract

During the COVID-19 pandemic, the use of alcohol-based hand sanitizers (ABHS) increased worldwide among the public as well as the health care workers in pursuit to prevent the spread of SARS-CoV-2, the causative virus of COVID-19. Hand hygiene is one of the primary preventive measures to prevent the spread of harmful germs. Although ABHS are effective hand hygiene products and help reduce the transmission of pathogenic microorganisms, appropriate use of such products is necessary to ensure the maximum killing of pathogens and to prevent hazards associated with ABHS. The effectiveness of ABHS against different microorganisms, including SARS-CoV-2 is also documented, but proper knowledge on hand hygiene techniques, selection of appropriate hand sanitizer product, and safe handling of ABHS are required to avoid their adverse effects such as allergies, skin irritation, lung injury, fire hazards, and toxicities. The effectiveness of ABHS is dependent on several factors including its appropriate usage, manufacturing methods, the choice of active agents, and the appropriateness of the agent on the target pathogen. This article highlights the importance of proper usage, handling, and appropriate ABHS selection for maximum efficacy against intended pathogens and safe use of ABHS. User awareness can help promote the appropriate usage of ABHS and prevent its hazards, which ultimately can help in preventing the transmission of pathogenic microorganisms.

摘要

在新冠疫情期间,为防止新冠病毒(SARS-CoV-2,即导致新冠肺炎的病原体)传播,全球公众以及医护人员对含酒精洗手液(ABHS)的使用量都有所增加。手部卫生是预防有害病菌传播的主要预防措施之一。虽然含酒精洗手液是有效的手部卫生用品,有助于减少病原微生物的传播,但正确使用此类产品对于确保最大程度杀灭病原体以及预防与含酒精洗手液相关的危害至关重要。含酒精洗手液对包括新冠病毒在内的不同微生物的有效性也有记录,但需要掌握正确的手部卫生技术知识、选择合适的洗手液产品以及安全使用含酒精洗手液,以避免其产生过敏、皮肤刺激、肺部损伤、火灾隐患和毒性等不良影响。含酒精洗手液的有效性取决于几个因素,包括其正确使用方法、制造工艺、活性剂的选择以及该活性剂对目标病原体的适用性。本文强调了正确使用、处理和选择合适的含酒精洗手液对于最大程度杀灭目标病原体以及安全使用含酒精洗手液的重要性。提高用户意识有助于促进含酒精洗手液的正确使用并预防其危害,最终有助于预防病原微生物的传播。

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