马来西亚吉兰丹一只城市老鼠中[具体物质]分子检测的首例病例报告：一项意外发现。 （注：原文中“of”后面缺少具体内容）
First case report on molecular detection of in an urban rat in Kelantan, Malaysia: An accidental finding.
作者信息
Kamaruzaman Intan Noor Aina, Ting Hong Wei, Mokhtar Muhammad Aiman Mohd, Yuan Yong Kai, Shah Azim Wafiy Gulam, Hamid Fathin Faahimaah Abdul, Zalati Che Wan Salma Che Wan, Shaharulnizim Nurshahirah, Reduan Mohd Farhan Hanif, Abu-Bakar Luqman
机构信息
Department of Paraclinical Studies, Faculty of Veterinary Medicine, Universiti Malaysia Kelantan, Kota Bharu, Kelantan, Malaysia.
Department of Clinical Studies, Faculty of Veterinary Medicine, Universiti Malaysia Kelantan, Kota Bharu, Kelantan, Malaysia.
出版信息
J Adv Vet Anim Res. 2021 Sep 19;8(3):435-439. doi: 10.5455/javar.2021.h531. eCollection 2021 Sep.
OBJECTIVE
This case report highlights the first detection of , a blood protozoan parasite found in an urban rat in Kota Bharu, Kelantan.
MATERIALS AND METHODS
Rat trapping was carried out within the Kota Bharu vicinity near a local wet market. A total of 38 rats were captured and subjected to peripheral blood smearing using Giemsa stain. Positive rats were sent for histopathological analysis for the evaluation of the organ samples.
RESULTS
The presence of trypanosomes was found in one sample from a blood smear. This was connected to a histological lesion on kidney tissues, which revealed a high concentration of trypanosomes. Additionally, the positive sample was confirmed as based on molecular diagnosis via polymerase chain reaction and subsequent sequencing and phylogenetic analysis.
CONCLUSIONS
This finding serves as a baseline for further surveillance on population among urban rats in Kelantan and possible zoonotic transmission to humans.
目的
本病例报告重点介绍了在吉兰丹哥打巴鲁市的一只城市大鼠中首次检测到的一种血液原生动物寄生虫。
材料与方法
在哥打巴鲁市当地湿货市场附近进行捕鼠。共捕获38只大鼠，并使用吉姆萨染色对其进行外周血涂片检查。对阳性大鼠的器官样本进行组织病理学分析以进行评估。
结果
在一张血涂片的一个样本中发现了锥虫。这与肾组织的组织学病变有关，该病变显示锥虫浓度很高。此外，通过聚合酶链反应进行分子诊断，随后进行测序和系统发育分析，确认阳性样本为[具体寄生虫名称未给出]。
结论
这一发现为进一步监测吉兰丹城市大鼠中的[具体寄生虫名称未给出]种群以及可能的人畜共患病传播给人类提供了基线。
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