Shaw Maddison, Lye Jessica, Alves Andrew, Keehan Stephanie, Lehmann Joerg, Hanlon Maximilian, Kenny John, Baines John, Porumb Claudiu, Geso Moshi, Brown Rhonda
Australian Clinical Dosimetry Service, Australian Radiation Protection and Nuclear Safety Agency, Yallambie, VIC, Australia.
School of Health and Biomedical Science, RMIT University, Melbourne, VIC, Australia.
Phys Imaging Radiat Oncol. 2021 Oct 19;20:40-45. doi: 10.1016/j.phro.2021.10.002. eCollection 2021 Oct.
Synthetic diamond detectors offer real time measurement of dose in radiotherapy applications which require high spatial resolution. Additional considerations and corrections are required for measurements where the diamond detector is orientated at various angles to the incident beam. This study investigated diamond detectors for end-to-end testing of Stereotactic Body Radiotherapy (SBRT) and Stereotactic Radiosurgery (SRS) in the context of dosimetry audits.
Seven individual diamond detectors were investigated and compared with respect to warm up stability, dose-rate dependence, linearity, detector shadowing, energy response, cross-calibration, angular dependence and positional sensitivity in SBRT and SRS.
Large variation in the cross calibration factors was found between the seven individual detectors. For each detector, the energy dependence in the cross calibration factor was on average <0.6% across the beam qualities investigated (Co-60 Gamma Knife, and MV beams with TPR 0.684-0.733). The angular corrections for individual fields were up to 5%, and varied with field size. However, the average angular dependence for all fields in a typical SRS treatment delivery was <1%. The overall measurement uncertainty was 3.6% and 3.1% (2σ) for an SRS and SBRT treatment plan respectively.
Synthetic diamond detectors were found to be reliable and robust for end-to-end dosimetry in SBRT and SRS applications. Orientation of the detector relative to the beam axis is an important consideration, as significant corrections are required for angular dependence.
合成金刚石探测器可在需要高空间分辨率的放射治疗应用中进行剂量实时测量。当金刚石探测器相对于入射束以不同角度定向时,测量需要额外的考虑和校正。本研究在剂量学审核的背景下,研究了用于立体定向体部放射治疗(SBRT)和立体定向放射外科手术(SRS)端到端测试的金刚石探测器。
研究了七个单独的金刚石探测器,并在SBRT和SRS中就预热稳定性、剂量率依赖性、线性、探测器阴影、能量响应、交叉校准、角度依赖性和位置敏感性进行了比较。
七个单独探测器之间的交叉校准因子存在很大差异。对于每个探测器,在所研究的束流质量(钴-60伽马刀以及TPR为0.684 - 0.733的兆伏级束流)范围内,交叉校准因子中的能量依赖性平均<0.6%。各个射野的角度校正高达5%,且随射野大小而变化。然而,在典型的SRS治疗投照中,所有射野的平均角度依赖性<1%。对于SRS和SBRT治疗计划,总体测量不确定度分别为3.6%和3.1%(2σ)。
发现合成金刚石探测器在SBRT和SRS应用中的端到端剂量测定方面可靠且稳健。探测器相对于束轴的方向是一个重要考虑因素,因为角度依赖性需要进行显著校正。