Animal Dental Center, Towson, MD, United States.
BluePearl Veterinary Partners-Midvale, Midvale, UT, United States.
J Vet Dent. 2021 Jun;38(2):93-98. doi: 10.1177/08987564211046393. Epub 2021 Nov 1.
Dentin dysplasia is an autosomal-dominant genetic abnormality that occurs in humans and results in diffuse radiographic dental abnormalities and variable tooth discoloration due to an underlying defect in secondary dentinogenesis. This case report presents distinctive radiographic and histopathologic dental abnormalities in a dog that are consistent with generalized dentin dysplasia. These findings are similar to but not completely analogous to any specific clinical type of dentin dysplasia in humans. Grossly, the majority of the teeth in this case were discolored and most were determined to be vital. Dentin dysplasia should be included in the list of differential diagnoses of discolored teeth and notably this form of discoloration does not necessarily indicate loss of vitality.
牙本质发育不全是一种常染色体显性遗传异常，发生于人类，表现为弥漫性的牙齿放射学异常和由于继发性牙本质生成缺陷导致的可变牙齿变色。本病例报告介绍了一只犬的具有特征性的放射学和组织病理学牙齿异常，符合弥漫性牙本质发育不全。这些发现与人类的任何特定临床类型的牙本质发育不全相似但不完全相同。大体上，该病例的大多数牙齿变色，大多数被认为是有活力的。牙本质发育不全应列入变色牙齿的鉴别诊断清单中，值得注意的是，这种形式的变色不一定表示活力丧失。
