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胫骨滑动弹性钉技术治疗中重度成骨不全症:长期结果。

Tibial Sliding Elastic Nailing Technique in Moderate-to-Severe Osteogenesis Imperfecta: Long-term Outcomes.

机构信息

Orthopaedics Surgery Department.

Department of Pediatric Genetics, Necker Hospital, Assistance Publique Hopitaux de Paris, University of Paris, Paris, France.

出版信息

J Pediatr Orthop. 2022 Jan 1;42(1):47-52. doi: 10.1097/BPO.0000000000001996.

Abstract

BACKGROUND

Osteosynthesis of leg fractures and deformities in children with osteogenesis imperfecta should align the skeleton and overcome its fragility during growth with a telescopic effect. A high rate of mechanical complications is associated with various surgical techniques described in the literature.

PURPOSE

The objective of this work was to assess the long-term clinical and radiologic outcomes of tibial sliding elastic nailing technique.

METHODS

A total of 22 children with an average age of 4.7 years were operated using the technique between 2004 and 2018 unilaterally (6) or bilaterally (16), that is, 38 operations. They were listed according to the Sillence classification into type I (3), III (17), or V (2). The nails were introduced percutaneously at the distal tibial epiphysis through the medial malleolus, and in the prespinal area for the proximal tibial epiphysis. The stainless-steel rods diameter was 1.5 to 2.5 mm, adapted to the size and weight of the patient. Realignment osteotomies were performed if necessary. Radiographic data including the correction of the deformation in the frontal and sagittal planes, as well as the width at mid-shaft of the tibia in the frontal and sagittal planes, were reviewed. Gillette Functional Score, assessment of pain, mechanical and infectious complications were collected.

RESULTS

The average follow-up was 8.6 years. In the frontal plane, preoperative average varus was 8 degrees (maximum, 40 degrees), 5 degrees (maximum, 13 degrees) postoperatively, and 6 degrees (maximum, 12 degrees) at last follow-up. Preoperative valgus was 11 degrees (maximum, 22 degrees), 9 degrees (maximum, 15 degrees) postoperatively, and 9 degrees (maximum, 14 degrees) at the last follow-up. In the sagittal plane, the mean sagittal bowling of the tibia was 32 degrees (4 to 75 degrees) preoperatively, 9 degree (1 to 26 degrees) postoperatively, and 9 degrees (1 to 24 degrees) at last follow-up. The width at mid-shaft of the tibia in the frontal plane was 1.1 cm (0.6 to 1.8 cm) preoperatively and 1.3 cm at the last follow-up (0.7 to 2.0 cm). In the sagittal plane, it was 1.25 cm (0.7 to 2.7 cm) preoperatively and 1.27 cm (0.8 to 2.8 cm) at the last follow-up. Ten patients did not require revision surgery during their follow-up. Sixteen mechanical complications occurred in 12 patients (12 fractures or deformities following a lack of overlap of the 2 rods at an average time of 4.9 years after the initial surgery, 3 prominence of the nail, 1 pseudarthrosis). No infectious complication was reported. Gillette Functional Score was 20.54/65. Fifteen patients were able to walk at last follow-up, and 18 had no painful discomfort.

CONCLUSIONS

The tibial sliding elastic nailing technique provides satisfactory clinical and radiologic results over time. Performed in case of fracture or as a preventive treatment, it allows a good correction of angular deformations. It is particularly suitable for young patients with a narrow medullary shaft.

LEVEL OF EVIDENCE

Level IV-therapeutic study.

摘要

背景

成骨不全症儿童腿部骨折和畸形的骨愈合,应在骨骼生长过程中保持骨骼的对齐并克服其脆弱性,同时发挥伸缩作用。各种文献中描述的手术技术都与较高的机械并发症发生率有关。

目的

本研究旨在评估胫骨滑动弹性钉技术的长期临床和影像学结果。

方法

2004 年至 2018 年,22 例儿童(平均年龄 4.7 岁)单侧(6 例)或双侧(16 例)接受了该技术治疗,共 38 例手术。根据 Sillence 分类,他们被分为 I 型(3 例)、III 型(17 例)或 V 型(2 例)。将不锈钢棒经内踝经皮插入胫骨远端干骺端,在脊柱前区插入胫骨近端干骺端。棒的直径为 1.5 至 2.5 毫米,适应患者的体型和体重。如果需要,进行矫正截骨术。回顾了包括在额状面和矢状面纠正畸形以及在额状面和矢状面胫骨中段宽度在内的影像学数据。收集了 Gillette 功能评分、疼痛评估、机械和感染并发症。

结果

平均随访 8.6 年。在额状面,术前平均内翻 8 度(最大 40 度),术后 5 度(最大 13 度),末次随访时 6 度(最大 12 度)。术前外翻 11 度(最大 22 度),术后 9 度(最大 15 度),末次随访时 9 度(最大 14 度)。在矢状面,胫骨矢状位弯曲的平均斜率为 32 度(4 至 75 度),术后为 9 度(1 至 26 度),末次随访时为 9 度(1 至 24 度)。胫骨中段在额状面的宽度为 1.1 厘米(0.6 至 1.8 厘米),末次随访时为 1.3 厘米(0.7 至 2.0 厘米)。在矢状面,术前为 1.25 厘米(0.7 至 2.7 厘米),末次随访时为 1.27 厘米(0.8 至 2.8 厘米)。10 例患者在随访期间未进行翻修手术。12 例患者中有 16 例发生机械并发症(12 例为 2 根棒重叠不足导致的骨折或畸形,平均在初次手术后 4.9 年发生,3 例为钉突出,1 例为假关节)。无感染并发症报告。Gillette 功能评分为 20.54/65。15 例患者末次随访时能够行走,18 例无疼痛不适。

结论

胫骨滑动弹性钉技术随时间推移可提供满意的临床和影像学结果。作为骨折后的治疗方法或预防性治疗方法,它可以很好地纠正角度畸形。它特别适用于骨髓腔狭窄的年轻患者。

证据等级

IV 级-治疗研究。

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