Azeez Luqmon, Aremu Harun K, Olabode Olalekan A
Department of Pure and Applied Chemistry, Osun State University, Osogbo, Nigeria.
Department of Biochemistry, Osun State University, Osogbo, Nigeria.
Bull Environ Contam Toxicol. 2022 Apr;108(4):694-701. doi: 10.1007/s00128-021-03403-4. Epub 2021 Nov 1.
This study reports the implications of silver nanoparticles (AgNPs) and cow-dung contamination on water quality and oxidative perturbations in antioxidant biomarkers in the exposed Clarias gariepinus. Sixteen samples of C. gariepinus were exposed to fresh-water, 0.75 mg/mL each of AgNPs, cow-dung and a mixture of AgNPs-cow dung dosed water for 10 days. Cow-dung significantly (p < 0.05) depleted dissolved oxygen (DO) and increased biochemical oxygen demand (BOD) by 14% and 75% respectively. The trends of abundance and bioaccumulation of Ag in C. gariepinus exposed to different treatments followed kidney > muscle > gill > liver, implying the kidney was the worst affected organ. The AgNPs significantly (p < 0.05) perturbed vital organs in C. gariepinus by altering activities of antioxidant biomarkers, whereas AgNPs-cow dung had reduced perturbations implying organic matter bound Ag to reduce toxicity. These results conclude that AgNPs posed a challenging environment for C. gariepinus to thrive.
本研究报告了银纳米颗粒（AgNPs）和牛粪污染对暴露的尖吻鲈抗氧化生物标志物中水质和氧化扰动的影响。16个尖吻鲈样本分别暴露于淡水、浓度均为0.75毫克/毫升的AgNPs、牛粪以及AgNPs与牛粪混合的加药水中，持续10天。牛粪显著（p < 0.05）降低了溶解氧（DO），并分别使生化需氧量（BOD）增加了14%和75%。暴露于不同处理的尖吻鲈体内Ag的丰度和生物累积趋势为肾脏 > 肌肉 > 鳃 > 肝脏，这意味着肾脏是受影响最严重的器官。AgNPs通过改变抗氧化生物标志物的活性，显著（p < 0.05）扰乱了尖吻鲈的重要器官，而AgNPs与牛粪的混合物造成的扰动较小，这意味着有机物结合的Ag降低了毒性。这些结果表明，AgNPs对尖吻鲈的生存构成了具有挑战性的环境。
