Department of Zoology, Faculty of Science, Assiut University, Assiut 71516, Egypt.
Department of Zoology, Faculty of Science, Assiut University, Assiut 71516, Egypt.
Ecotoxicol Environ Saf. 2019 Apr 30;171:638-646. doi: 10.1016/j.ecoenv.2019.01.011. Epub 2019 Jan 15.
The present study investigates the hemotoxic and cytotoxic impacts of two acute doses of silver nanoparticles (AgNPs) on the African catfish, Clarias garepinus in comparison to the impact of AgNO and the control fish. AgNPs-induced impacts were recorded on some biological and hematological indices of that species on the bases of their size (20 and 40 nm) and concentration (10 and 100 µg) but no significant interaction. AgNO had very low impact on these indices in comparison to AgNPs. Recovery period for 15 days was found to be valid to remove AgNPs and AgNO toxicity for most indices. The condition factor exhibited stability under stress whereas the hepatosomatic index was more sensitive to AgNPs. The AgNPs-induced hematological changes recorded were corresponding with different blood cell alterations which increased in frequency from the control and AgNO to 40 nm/100 µg; such blood cell alterations disappeared to great extent after recovery period of 15-days in a reverse order.
本研究调查了两种急性剂量的银纳米粒子 (AgNPs) 对非洲鲶鱼 (Clarias gariepinus) 的血液毒性和细胞毒性影响，并与 AgNO 和对照组鱼进行了比较。根据 AgNPs 的大小 (20 和 40nm) 和浓度 (10 和 100µg)，记录了 AgNPs 对该物种的一些生物和血液学指标的影响，但没有显著的相互作用。与 AgNPs 相比，AgNO 对这些指标的影响很小。发现 15 天的恢复期可有效去除 AgNPs 和 AgNO 的毒性，大多数指标都能得到恢复。在应激条件下，体况系数表现出稳定性，而肝体比指数对 AgNPs 更为敏感。AgNPs 引起的血液学变化与不同的血细胞变化相对应，从对照组和 AgNO 到 40nm/100µg ，血细胞变化的频率增加；经过 15 天的恢复期后，这种血细胞变化在很大程度上按相反的顺序消失。
