Department of Radiology, Southwest Hospital, Third Military Medical University(Army Medical University), Chongqing, 400038, China.
Department of Radiology, Chenggu County Hospital, Hanzhong, 723200, China.
BMC Musculoskelet Disord. 2021 Nov 1;22(1):919. doi: 10.1186/s12891-021-04716-5.
Bone marrow edema of the sacroiliac joint is the early imaging manifestation, an indicator of inflammatory activity of ankylosing spondylitis (AS) (Yang R, et. al. Medicine (Baltimore) 98:e14620, 2019).
The aim of the study was to investigate the value of magnetic resonance imaging (MRI) Dixon sequence in the diagnosis of marrow edema of the sacroiliac joint in patients with AS.
Forty-five patients with AS admitted in our hospital between November 2016 and February 2019 were selected retrospectively as the case group. Forty-five healthy subjects recruited between November 2016 and February 2019 served as the control group. Bath ankylosing spondylitis disease activity index (BASDAI), Bath ankylosing spondylitis functional index (BASFI), C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were recorded after admission to the hospital. The Dixon sequence water-fat ratio of the iliac and sacral surfaces of the bilateral sacroiliac joints in the study group were compared with indicators above in order to find the correlation.
The water-fat ratio under the bilateral sacroiliac joints on Dixon sequence images in the case group was significantly higher than that in the healthy control group (P<0.05). The Dixon sequence water-fat ratio of the iliac and sacral surfaces of the bilateral sacroiliac joints in the study group were positively correlated with spinal arthritis research (SPARCC), BASFI and BASDAI score (all P < 0.05), but did not correlate with ESR and CRP.
The water-fat ratio of magnetic resonance Dixon sequence can be used as a reference index to evaluate the degree of bone marrow edema in active stage of sacroiliac arthritis.
骨髓水肿是骶髂关节的早期影像学表现，是强直性脊柱炎（AS）炎症活动的指标（Yang R，等。Medicine（巴尔的摩）98:e14620，2019）。
本研究旨在探讨磁共振成像（MRI） Dixon 序列在诊断 AS 患者骶髂关节骨髓水肿中的价值。
回顾性选取 2016 年 11 月至 2019 年 2 月我院收治的 45 例 AS 患者作为病例组。同期选取 45 名健康志愿者作为对照组。入院后记录 Bath 强直性脊柱炎疾病活动指数（BASDAI）、Bath 强直性脊柱炎功能指数（BASFI）、C 反应蛋白（CRP）和红细胞沉降率（ESR）。比较病例组双侧骶髂关节髂骨和骶骨表面 Dixon 序列的水脂比与上述指标的相关性。
病例组双侧骶髂关节 Dixon 序列图像下水脂比值明显高于健康对照组（P<0.05）。病例组双侧骶髂关节髂骨和骶骨表面 Dixon 序列水脂比值与脊柱关节炎研究协会评分（SPARCC）、BASFI 和 BASDAI 评分呈正相关（均 P<0.05），但与 ESR 和 CRP 无相关性。
磁共振 Dixon 序列水脂比值可作为评估骶髂关节炎活动期骨髓水肿程度的参考指标。
