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轴性脊柱关节炎影像学的最新进展与见解

Recent advances and insights into imaging of axial spondyloarthritis.

作者信息

Lambert Robert G W, Tuite Michael J

机构信息

Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada.

Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

出版信息

Skeletal Radiol. 2025 Mar 6. doi: 10.1007/s00256-025-04899-1.

DOI:10.1007/s00256-025-04899-1
PMID:40047906
Abstract

Imaging of the axial skeleton is a critical component of the diagnosis, management and follow-up of axial spondyloarthritis which may be difficult on clinical grounds and biological data alone. The sacroiliac joints (SIJ) are anatomically complex with high incidence of normal variation and degenerative change and techniques used to image the SIJ vary widely. Interpretation of MRI scans of the axial skeleton is facilitated by employing consistent protocols in which sequences are designed for the sensitive detection of inflammatory lesions, fat metaplasia and bone erosion. Considerable research has been undertaken in recent years to improve the accuracy of detection of these findings in early disease and detection of structural damage changes that would allow improvements in diagnosis and management of SpA patients. This review will examine recent advances in our understanding of axSpA and discuss innovations in MRI and CT, focusing on how to optimize a standard acquisition protocol for MRI of the SIJ, and discussing how to avoid some common technical pitfalls that may be encountered in MRI clinical practice.

摘要

中轴骨骼成像对于中轴型脊柱关节炎的诊断、管理及随访至关重要,仅依据临床症状和生物学数据可能难以诊断。骶髂关节(SIJ)解剖结构复杂,正常变异和退行性改变发生率高,用于骶髂关节成像的技术差异很大。采用一致的方案有助于对中轴骨骼的MRI扫描进行解读,其中序列设计用于灵敏检测炎症性病变、脂肪化生和骨质侵蚀。近年来开展了大量研究,以提高早期疾病中这些表现的检测准确性,以及检测结构损伤变化,从而改善脊柱关节炎(SpA)患者的诊断和管理。本综述将探讨我们对中轴型脊柱关节炎(axSpA)认识的最新进展,并讨论MRI和CT的创新之处,重点关注如何优化骶髂关节MRI的标准采集方案,以及讨论如何避免MRI临床实践中可能遇到的一些常见技术陷阱。

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本文引用的文献

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Development of international consensus on a standardised image acquisition protocol for diagnostic evaluation of the sacroiliac joints by MRI: an ASAS-SPARTAN collaboration.制定用于 MRI 诊断评估骶髂关节的标准化图像采集协议的国际共识发展:ASAS-SPARTAN 合作。
Ann Rheum Dis. 2024 Nov 14;83(12):1628-1635. doi: 10.1136/ard-2024-225882.
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Detection of structural lesions of the sacroiliac joints in patients with spondyloarthritis: A comparison of T1-weighted 3D spoiled gradient echo MRI and MRI-based synthetic CT versus T1-weighted turbo spin echo MRI.
检测强直性脊柱炎患者骶髂关节的结构病变:T1 加权 3D 扰相梯度回波 MRI 和基于 MRI 的合成 CT 与 T1 加权 turbo 自旋回波 MRI 的比较。
Skeletal Radiol. 2024 Nov;53(11):2459-2468. doi: 10.1007/s00256-024-04669-5. Epub 2024 Apr 9.
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The sacroiliac joint across ages - what is normal?不同年龄段的骶髂关节——正常情况是怎样的?
Ther Adv Musculoskelet Dis. 2024 Mar 29;16:1759720X241241126. doi: 10.1177/1759720X241241126. eCollection 2024.
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MRI-based synthetic CT: a new method for structural damage assessment in the spine in patients with axial spondyloarthritis - a comparison with low-dose CT and radiography.基于 MRI 的合成 CT:一种用于评估中轴型脊柱关节炎患者脊柱结构损伤的新方法——与低剂量 CT 和 X 射线摄影的比较。
Ann Rheum Dis. 2024 May 15;83(6):807-815. doi: 10.1136/ard-2023-225444.
6
ESR Essentials: Imaging of sacroiliitis-practice recommendations by ESSR.ESR 精华:中轴型脊柱关节炎影像学-ESR 实践推荐
Eur Radiol. 2024 Sep;34(9):5773-5782. doi: 10.1007/s00330-024-10653-3. Epub 2024 Mar 9.
7
Accuracy of dual-energy computed tomography for bone marrow edema in the sacroiliac joint: A systematic review and meta-analysis.双能 CT 对骶髂关节骨髓水肿的诊断准确性:系统评价和荟萃分析。
Medicine (Baltimore). 2024 Jan 5;103(1):e36708. doi: 10.1097/MD.0000000000036708.
8
Fatty Acids Composition of the Sacroiliac Joint in Axial Spondyloarthritis: Analysis Using 3.0 T Chemical Shift-Encoded MRI.轴向型脊柱关节炎骶髂关节的脂肪酸成分:采用 3.0T 化学位移编码 MRI 分析。
J Magn Reson Imaging. 2024 Sep;60(3):1027-1034. doi: 10.1002/jmri.29170. Epub 2023 Dec 5.
9
Performances of machine learning algorithms in discriminating sacroiliitis features on MRI: a systematic review.机器学习算法在 MRI 鉴别骶髂关节炎特征中的性能:系统评价。
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Measuring response to treatment in axial spondyloarthritis using quantitative imaging biomarkers: a prospective observational cohort study.使用定量成像生物标志物测量中轴型脊柱关节炎的治疗反应:一项前瞻性观察队列研究。
Br J Radiol. 2023 Dec;96(1152):20220530. doi: 10.1259/bjr.20220530. Epub 2023 Oct 25.