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PSMA Expression Assessed by PET Imaging Is a Required Biomarker for Selecting Patients for Any PSMA-Targeted Therapy.

作者信息

Calais Jeremie, Czernin Johannes

机构信息

David Geffen School of Medicine at UCLA, Los Angeles, California.

出版信息

J Nucl Med. 2021 Nov;62(11):1489-1491. doi: 10.2967/jnumed.121.263159.

DOI:10.2967/jnumed.121.263159
PMID:34725231
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8612346/
Abstract
摘要

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To Scan or Not to Scan: An Unnecessary Dilemma for PSMA Radioligand Therapy.扫描与否：PSMA放射性配体疗法中不必要的困境
J Nucl Med. 2021 Nov;62(11):1487-1488. doi: 10.2967/jnumed.121.263035. Epub 2021 Aug 26.
2
What's behind Ga-PSMA-11 uptake in primary prostate cancer PET? Investigation of histopathological parameters and immunohistochemical PSMA expression patterns.Ga-PSMA-11 在原发性前列腺癌 PET 中的摄取背后是什么？对组织病理学参数和免疫组织化学 PSMA 表达模式的调查。
Eur J Nucl Med Mol Imaging. 2021 Nov;48(12):4042-4053. doi: 10.1007/s00259-021-05501-1. Epub 2021 Aug 13.
3
Nomograms to predict outcomes after Lu-PSMA therapy in men with metastatic castration-resistant prostate cancer: an international, multicentre, retrospective study.Lu-PSMA 治疗转移性去势抵抗性前列腺癌患者预后的列线图：一项国际多中心回顾性研究。
Lancet Oncol. 2021 Aug;22(8):1115-1125. doi: 10.1016/S1470-2045(21)00274-6. Epub 2021 Jul 8.
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Lutetium-177-PSMA-617 for Metastatic Castration-Resistant Prostate Cancer.镥 177-PSMA-617 治疗转移性去势抵抗性前列腺癌。
N Engl J Med. 2021 Sep 16;385(12):1091-1103. doi: 10.1056/NEJMoa2107322. Epub 2021 Jun 23.
5
[Lu]Lu-PSMA-617 versus cabazitaxel in patients with metastatic castration-resistant prostate cancer (TheraP): a randomised, open-label, phase 2 trial.[吕]Lu-PSMA-617 对比卡巴他赛用于转移性去势抵抗性前列腺癌（TheraP）患者：一项随机、开放标签、2 期试验。
Lancet. 2021 Feb 27;397(10276):797-804. doi: 10.1016/S0140-6736(21)00237-3. Epub 2021 Feb 11.
6
Imaging expression of prostate-specific membrane antigen and response to PSMA-targeted β-emitting radionuclide therapies in metastatic castration-resistant prostate cancer.前列腺特异性膜抗原的影像学表现与转移性去势抵抗性前列腺癌对 PSMA 靶向β发射放射性核素治疗的反应
Prostate. 2021 Apr;81(5):279-285. doi: 10.1002/pros.24104. Epub 2021 Jan 19.
7
Prognostic implications of dual tracer PET/CT: PSMA ligand and [F]FDG PET/CT in patients undergoing [Lu]PSMA radioligand therapy.双示踪剂 PET/CT 的预后意义：PSMA 配体和 [F]FDG PET/CT 在接受 [Lu]PSMA 放射性配体治疗的患者中的应用。
Eur J Nucl Med Mol Imaging. 2021 Jun;48(6):2024-2030. doi: 10.1007/s00259-020-05160-8. Epub 2020 Dec 18.
8
Analysis of PSMA expression and outcome in patients with advanced Prostate Cancer receiving Lu-PSMA-617 Radioligand Therapy.接受 Lu-PSMA-617 放射性配体治疗的晚期前列腺癌患者中 PSMA 表达与结局分析。
Theranostics. 2020 Jun 19;10(17):7812-7820. doi: 10.7150/thno.47251. eCollection 2020.
9
Prognostic biomarkers in men with metastatic castration-resistant prostate cancer receiving [177Lu]-PSMA-617.接受[177Lu]-PSMA-617治疗的转移性去势抵抗性前列腺癌男性患者的预后生物标志物
Eur J Nucl Med Mol Imaging. 2020 Sep;47(10):2322-2327. doi: 10.1007/s00259-020-04723-z. Epub 2020 Mar 5.
10
Investigating PSMA-Targeted Radioligand Therapy Efficacy as a Function of Cellular PSMA Levels and Intratumoral PSMA Heterogeneity.研究 PSMA 靶向放射性配体治疗的疗效与细胞 PSMA 水平和肿瘤内 PSMA 异质性的关系。
Clin Cancer Res. 2020 Jun 15;26(12):2946-2955. doi: 10.1158/1078-0432.CCR-19-1485. Epub 2020 Jan 13.