Department of Medicine, University of Vermont College of Medicine, Burlington, Vermont, USA.
University of Vermont College of Medicine, Burlington, VT, USA.
BMJ Paediatr Open. 2021 Oct 27;5(1):e001259. doi: 10.1136/bmjpo-2021-001259. eCollection 2021.
Reduced symptomatology and access to testing in children have led to underestimates of paediatric COVID-19 prevalence and raised concerns about school safety. To explore COVID-19 prevalence and risk factors in school settings, we conducted a SARS-CoV-2 serosurvey in a Vermont, USA school district in December 2020. Among 336 students (63%) and 196 teachers/staff (37%), adjusted seroprevalence was 4.7% (95% CI 2.9 to 7.2) and was lowest in preK-5 students (4-10 Years). Seroprevalence was 10-fold higher than corresponding state PCR data but was low overall with no evidence of onward transmissions. These results further support feasibility of in-person learning during COVID-19 with appropriate mitigation measures.
儿童症状减轻和检测机会减少，导致对儿科 COVID-19 患病率的低估，并对学校安全产生担忧。为了探索学校环境中的 COVID-19 患病率和危险因素，我们于 2020 年 12 月在美国佛蒙特州的一个学区进行了 SARS-CoV-2 血清学调查。在 336 名学生（63%）和 196 名教师/工作人员（37%）中，调整后的血清阳性率为 4.7%（95%CI 2.9 至 7.2），学前班至 5 年级学生（4-10 岁）的血清阳性率最低。血清阳性率比相应的州 PCR 数据高 10 倍，但总体上较低，没有进一步传播的证据。这些结果进一步支持在 COVID-19 期间采取适当缓解措施进行面对面学习的可行性。
