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颅骨修复术的广阔世界:一项多中心回顾性研究和基于患者个体化的治疗流程图。

The Boundless World of Cranioplasty: A Multicenter Retrospective Study and Therapeutic Flow-Chart Patient-Specific Based.

机构信息

Department of Experimental Biomedicine and Clinical Neurosciences, School of Medicine, Postgraduate Residency Program in Neurological Surgery, Neurosurgical Clinic, AOUP "Paolo Giaccone," Palermo.

Department of Neurosurgery, Highly Specialized Hospital and of National Importance "Garibaldi," Catania.

出版信息

J Craniofac Surg. 2021;32(8):2758-2762. doi: 10.1097/SCS.0000000000007903.

Abstract

BACKGROUND

Cranioplasty is both a functional and aesthetical therapeutic option. In the clinical scenario every cranioplasty's material is potentially qualified to achieve the goal of calvarian reconstruction but there is a lack of agreement about the optimum choice, especially between the heterologous ones. The choice of cranioplasty widely depends on surgeon's personal preferences. In this retrospective multicentric study a comparative analysis of hydroxyapatite or titanium cranioplasties was carried on analyzing the main factors considered by the surgeon to choose a material rather than another one. Our results and data were compared with those reported in the scientific literature and a flow-chart regarding the therapeutic approach in the choice of the most suitable cranioplasty was proposed and discussed.

METHODS

The authors present a multicentric study considering 2 groups of patients who underwent 2 different kinds of cranioplasty: hydroxyapatite and titanium. The outcomes measures included the surgical timing and the maintenance of post-operative subgaleal drain.

RESULTS

A total of 40 patients that had cranioplasty treatment were evaluated. The surgical technique was analyzed. In patients that underwent titanium cranioplasty we observed a reduction in the operative times and in subgaleal drain maintenance. In relation to the age, comorbidity, and neurological status a score, called most suitable material (MSM), was elaborated and a therapeutic algorithm is proposed.

CONCLUSIONS

This study confirms the known advantages and drawback of titanium and hydroxyapatite prostheses. Thanks to the lessons learned from our experience on this field, we elaborated the MSM score that coupled with the therapeutic flow-chart proposed could address the choice of the MSM for a specific patient.

摘要

背景

颅骨修复术既是一种功能性的,也是一种美学治疗选择。在临床情况下,每一种颅骨修复材料都有可能达到颅骨重建的目标,但对于最佳选择,尤其是异体材料,还存在着缺乏共识的问题。颅骨修复术的选择在很大程度上取决于外科医生的个人喜好。在这项回顾性多中心研究中,对羟基磷灰石或钛颅骨修复术进行了比较分析,分析了外科医生选择一种材料而不是另一种材料的主要因素。我们的结果和数据与科学文献中的报告进行了比较,并提出和讨论了一种关于治疗方法的流程图,以选择最合适的颅骨修复术。

方法

作者提出了一项多中心研究,考虑了两组接受两种不同类型颅骨修复术的患者:羟基磷灰石和钛。主要观察指标包括手术时机和术后皮下引流管的维持。

结果

共评估了 40 例接受颅骨修复治疗的患者。分析了手术技术。在接受钛颅骨修复术的患者中,我们观察到手术时间和皮下引流管维持时间减少。根据年龄、合并症和神经状态,制定了一个称为最合适材料(MSM)的评分,并提出了一个治疗算法。

结论

这项研究证实了钛和羟基磷灰石假体的已知优缺点。通过从我们在这一领域的经验中吸取的教训,我们制定了 MSM 评分,结合所提出的治疗流程图,可以为特定患者选择最合适的 MSM。

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