Semel Institute for Neuroscience and Human Behavior - Center for Community Health, 8783University of California, Los Angeles, CA, USA.
310750National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Int J STD AIDS. 2022 Feb;33(2):164-172. doi: 10.1177/09564624211053430. Epub 2021 Nov 2.
People living with HIV who use drugs (PLHWUD) face enormous challenges to access antiretroviral therapy (ART), addiction treatment, and other healthcare services. This study evaluated the effect of a community capacity-building approach on PLHWUD's access to healthcare services.
A cluster randomized controlled trial was conducted in four provinces of Vietnam. Trained commune health workers in the intervention condition were encouraged to provide services to PLHWUD in the community and engage them in HIV/addiction treatment and care using learned knowledge and skills. A total of 241 PLHWUD participated in surveys at the baseline and every three months for one year. The primary outcome was PLHWUD's reported barriers to seeking healthcare. A linear mixed-effects regression model with a difference in difference approach was used to estimate the intervention effect on the primary outcome.
Adjusted analyses indicated that significant intervention effects were observed at the Sixth and ninth month follow-ups for those on ART at the baseline and increased motivation to engage in treatment at the 3-month follow-up (60.2% vs 34.4% for the intervention and control groups, respectively).
The community capacity-building intervention had shown promising yet limited outcomes among a subset of PLHWUD in the community, that is, PLHWUD who had already initiated ART.
感染艾滋病病毒并同时吸毒的人群(PLHWUD)在获得抗逆转录病毒治疗(ART)、戒毒治疗和其他医疗保健服务方面面临巨大挑战。本研究评估了一种社区能力建设方法对 PLHWUD 获得医疗保健服务的影响。
在越南的四个省份进行了一项整群随机对照试验。在干预条件下,受过培训的社区卫生工作者被鼓励在社区中为 PLHWUD 提供服务,并利用所学的知识和技能,让他们参与 HIV/戒毒治疗和护理。共有 241 名 PLHWUD 在基线和一年中的每三个月进行了调查。主要结果是 PLHWUD 报告的寻求医疗保健的障碍。采用差分差分线性混合效应回归模型估计干预对主要结果的影响。
调整分析表明,在基线时已接受 ART 的人群在第六和第九个月的随访中以及在 3 个月的随访中增加了接受治疗的动机方面,干预有显著效果(干预组为 60.2%,对照组为 34.4%)。
社区能力建设干预在社区中已经开始接受 ART 的 PLHWUD 亚组中显示出了有希望但有限的结果。