Chen Jie, Zhang Bo
Department of Ultrasound,China-Japan Friendship Hospital,Beijing 100029,China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2021 Oct;43(5):827-832. doi: 10.3881/j.issn.1000-503X.12688.
The incidence of non-alcoholic fatty liver disease(NAFLD)keeps on rise.Without intervention,it may develop to steatohepatitis,cirrhosis,and even hepatocellular carcinoma.Liver biopsy,the gold standard for evaluating the steatosis severity of NAFLD,is invasive and unsuitable for large-scale screening.In recent years,magnetic resonance imaging(MRI)-related examinations have been used as a gold standard only second to liver biopsy,which still have disadvantages in large-scale application.Ultrasound has the advantages of simple operation,low cost,and safety,and may become an important method for accessing NALFD.This review summarizes the current studies about the diagnosis of liver steatosis by quantitative ultrasound assessment,including controlled attenuation parameters,attenuation imaging,ultrasonic liver/kidney intensity ratio and liver attenuation rate,and integrated backscatter.
非酒精性脂肪性肝病（NAFLD）的发病率持续上升。若不加以干预，它可能发展为脂肪性肝炎、肝硬化，甚至肝细胞癌。肝脏活检作为评估NAFLD脂肪变性严重程度的金标准，具有侵入性，不适用于大规模筛查。近年来，磁共振成像（MRI）相关检查仅被用作仅次于肝脏活检的金标准，但在大规模应用中仍存在缺点。超声具有操作简便、成本低和安全性高的优点，可能成为评估NAFLD的重要方法。本文综述了目前关于通过定量超声评估诊断肝脏脂肪变性的研究，包括受控衰减参数、衰减成像、超声肝脏/肾脏强度比和肝脏衰减率以及集成背向散射。
