Tian Jiao, Xu Yong-Sheng
Graduate School of Tianjin Medical University,Tianjin 300070,China.
Respiratory Department of Tianjin Children's Hospital,Tianjin 300074,China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2021 Oct;43(5):833-839. doi: 10.3881/j.issn.1000-503X.11953.
Bronchial asthma is a common chronic respiratory disease,and its diagnosis is mainly based on symptoms,signs,and pulmonary function test.Wheezing is a major symptom of asthma attack,which shows no obvious sign in the early stage while appears after the disease has progressed.Therefore,bronchial asthma is difficult to be detected in early stages,which often leads to worsening of the disease conditions.Pulmonary function test can effectively monitor upper and lower airway abnormalities and is currently the main means for monitoring asthma.However,its accuracy is highly dependent on patient's motivation and cooperation,which obviously limits the scope of application,especially for preschoolers and infants.Hence,there is an urgent need for a new technology with the function of long-term breath sound monitoring and automatic breathing detection to overcome the existing clinical deficiencies.Breath sound analysis emerges in the era of medical artificial intelligence,which can digitally process and convert the collected respiratory sounds by using a variety of different methods to form characteristic signal parameters and model the relationship between parameters and diseases.As we know,breath sounds are closely related to airway changes,and thus the detection and analysis of the sounds can provide reliable clinical information for the progress and control evaluation of asthma.This review mainly summaries the research progress of respiratory sound analysis in recent years,hoping to provide reference for further research.
支气管哮喘是一种常见的慢性呼吸道疾病,其诊断主要基于症状、体征和肺功能检查。哮鸣是哮喘发作的主要症状,早期无明显体征,疾病进展后才会出现。因此,支气管哮喘在早期难以被检测到,这常常导致病情恶化。肺功能检查可以有效监测上下气道异常,是目前监测哮喘的主要手段。然而,其准确性高度依赖于患者的积极性和配合度,这明显限制了其应用范围,尤其是对于学龄前儿童和婴儿。因此,迫切需要一种具有长期呼吸音监测和自动呼吸检测功能的新技术来克服现有的临床缺陷。呼吸音分析在医学人工智能时代应运而生,它可以通过多种不同方法对收集到的呼吸音进行数字处理和转换,形成特征信号参数,并对参数与疾病之间的关系进行建模。众所周知,呼吸音与气道变化密切相关,因此对呼吸音的检测和分析可以为哮喘的进展和控制评估提供可靠的临床信息。本综述主要总结了近年来呼吸音分析的研究进展,希望为进一步的研究提供参考。