Servicio de Pediatría, Enfermedades Infecciosas y Tropicales, Hospital Universitario La Paz, Madrid, Spain; Red de Investigación traslacional en infectología Pediátrica (RITIP), Spain.
Red de Investigación traslacional en infectología Pediátrica (RITIP), Spain; Unidad de Pediatría Investigación y Ensayos Clínicos (UPIC), Instituto de Investigación Sanitaria Hospital 12 de Octubre (IMAS12), Madrid; Fundación para la Investigación Biomédica del Hospital 12 de Octubre, Madrid; Servicio de Pediatría, Hospital Universitario Infanta Sofía, Universidad Europea de Madrid, Madrid, Spain.
An Pediatr (Engl Ed). 2021 Nov;95(5):382.e1-382.e8. doi: 10.1016/j.anpede.2021.10.002. Epub 2021 Oct 21.
Since the COVID-19 pandemic was declared in March 2020, we have learned a lot about the SARS-CoV-2 coronavirus, and its role in pediatric pathology. Children are infected in a rate quite similar to adults, although in most cases they suffer mild or asymptomatic symptoms. Around 1% of those infected require hospitalization, less than 0.02% require intensive care, and mortality is very low and generally in children with comorbidities. The most common clinical diagnoses are upper or lower respiratory infections, gastrointestinal infection and, more seriously, multisystemic inflammatory syndrome (MIS-C). Most episodes do not require treatment, except for MIS-C. Remdesivir has been widely used as a compassionate treatment and its role has yet to be defined. The newborn can become infected, although vertical transmission is very low (<1%) and it has been shown that the baby can safely cohabit with its mother and be breastfed. In general, neonatal infections have been mild. Primary care has supported a very important part of the management of the pandemic in pediatrics. There has been numerous collateral damage derived from the difficulty of access to care and the isolation suffered by children. The mental health of the pediatric population has been seriously affected. Although it has been shown that schooling has not led to an increase in infections, but rather the opposite. It is essential to continue maintaining the security measures that make schools a safe place, so necessary not only for children's education, but for their health in general.
自 2020 年 3 月宣布 COVID-19 大流行以来,我们已经了解了很多关于 SARS-CoV-2 冠状病毒及其在儿科病理学中的作用。儿童的感染率与成人相当,尽管大多数情况下他们患有轻度或无症状症状。大约 1%的感染者需要住院治疗,不到 0.02%的感染者需要重症监护治疗,死亡率非常低,而且通常是在有合并症的儿童中。最常见的临床诊断是上呼吸道或下呼吸道感染、胃肠道感染,更严重的是,多系统炎症综合征(MIS-C)。大多数病例不需要治疗,除了 MIS-C。瑞德西韦已被广泛用作同情治疗药物,但其作用尚未确定。新生儿也可能被感染,尽管垂直传播率非常低(<1%),而且已经表明婴儿可以与母亲安全同居并母乳喂养。一般来说,新生儿感染是轻度的。初级保健在儿科大流行管理中发挥了非常重要的作用。由于难以获得护理和儿童遭受的隔离,导致了许多附带损害。儿科人群的心理健康受到了严重影响。尽管已经表明学校教育并没有导致感染增加,而是相反。继续保持使学校成为安全场所的安全措施至关重要,这不仅对儿童的教育至关重要,而且对他们的整体健康也至关重要。