Institute of Hydrobiology, Department of Ecology, Jinan University, Guangzhou 510632, PR China.
Institute of Hydrobiology, Department of Ecology, Jinan University, Guangzhou 510632, PR China.
Bioresour Technol. 2022 Jan;344(Pt B):126260. doi: 10.1016/j.biortech.2021.126260. Epub 2021 Oct 30.
Fucoxanthin has multiple beneficial effects on human health. However, an efficient cultivation strategy for hyper-production of microalgae-based fucoxanthin has been seldom achieved. Here, an auto-controlled photobioreactor (PBR) installed internal light-emitting diodes illumination with adjustable spectra ratio was firstly used to culture Odontella aurita. The results showed that red light (RL) was more suitable for cell growth and fucoxanthin accumulation than blue light (BL) and white light. The biomass and fucoxanthin production were further promoted by optimizing the ratios of RL and BL, with 8:2 giving the highest productivities of 570 and 9.41 mg L d, respectively, which is the highest fucoxanthin productivity ever reported under photoautotrophic cultivation. Pilot-scale cultivation demonstrated its promising feasibility in commercial fucoxanthin production. Our study represents a pioneering work of harnessing the PBR with internal illumination for hyper-production of microalgae-based fucoxanthin, and provides feasible strategies for high-efficient production of other value-added products in related species/strains.
岩藻黄质对人类健康有多种有益作用。然而，高效培养基于微藻的岩藻黄质的策略很少实现。在这里，首次使用内置发光二极管照明且光谱比值可调的自控光生物反应器（PBR）培养Odontella aurita。结果表明，与蓝光（BL）和白光相比，红光（RL）更适合细胞生长和岩藻黄质积累。通过优化 RL 和 BL 的比例进一步促进了生物量和岩藻黄质的生产，其中 8:2 的比例分别给出了最高的生产率 570 和 9.41mgL d，这是在光自养培养下报告的最高岩藻黄质生产率。中试规模的培养证明了其在商业岩藻黄质生产中的应用具有广阔的可行性。我们的研究代表了利用内置照明 PBR 进行微藻基岩藻黄质高产的开创性工作，并为相关物种/菌株的其他高附加值产品的高效生产提供了可行的策略。
